Bromoenol lactone

CAS 88070-98-8 MFCD00270871

化学结构图

88070-98-8
SMILES: O=C1O/C(/CCC1C1=CC=CC2C=CC=CC=21)=C/Br

化学属性

Mol. FormulaC16H13BrO2
Mol. Weight317.18

别名和识别编码

Chemical NameBromoenol lactone
Synonym BEL BEL E-6-(Bromoethylene)tetrahydro-3-(1-naphthyl)-2H-pyran-2-one E-6-(Bromoethylene)tetrahydro-3-(1-naphthyl)-2H-pyran-2-one
MDL NumberMFCD00270871
PubChem Substance ID24278257
CAS Number88070-98-8
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分类

  • A to C, B, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Chymotrypsin, α-, Chymotrypsin, alpha-, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, Lipids in Cell Signaling, Phospholipase Inhibitors, Phospholipid Metabolism, Protease Inhibitor Specificity Index, Protease Inhibitors
  • {SNA} A to C,
  • {SNA} A to C, B, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Chymotrypsin, α-, Chymotrypsin, alpha-,
  • {SNA} A to C,

相关文献及参考

  • [2]. Takuma T, et al. Role of Ca2+-independent phospholipase A2 in exocytosis of amylase from parotid acinar cells. J Biochem. 1997 Jun;121(6):1018-24.
  • Ackermann, E.J., Inhibition of macrophage Ca 2+ -independent phospholipase A 2 by bromoenol lactone and trifluoromethyl ketones. J. Biol. Chem. 270 , 445, (1995) 摘要
  • Balsinde, J., Dennis, E.A., Bromoenol lactone inhibits magnesium-dependent phosphatidate phosphohydrolase and blocks triacylglycerol biosynthesis in mouse P388D1 macrophages. J. Biol. Chem. 271 , 31937, (1996) 摘要
  • Daniels, S.B., Haloenol lactones: potent enzyme-activated irreversible inhibitors for α-chymotrypsin. J. Biol. Chem. 258 , 15046, (1983) 摘要
  • Hazen. S.L., et al., Suicide inhibition of canine myocardial cytosolic calcium-independent phospholipase A 2 . J. Biol. Chem. 266 , 7227-7232, (1991) 摘要
  • Malhotra, A., et al., Role Of Calcium-independent Phospholipase A2 In The Pathogenesis Of Barth Syndrome. Proc. Natl

安全信息

WGK Germany3
GHS Symbol
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
Signal word Warning
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Hazard Codes Xi
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性

系列性分类


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