27-Hydroxycholesterol 27-羟基胆固醇

CAS 20380-11-4 MFCD00272990

化学结构图

20380-11-4
SMILES: C[C@]12CC[C@H]3[C@@H](CC=C4C[C@@H](O)CC[C@@]43C)[C@@H]1CC[C@@H]2[C@H](C)CCC[C@@H](C)CO

化学属性

Mol. FormulaC27H46O2
Mol. Weight402.65
Density1.03

别名和识别编码

Chemical Name27-Hydroxycholesterol
CAS Number20380-11-4
Synonym 5,25R-胆甾烯-3beta,26-二醇
Chemical Name Translation27-羟基胆固醇
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相关文献及参考

  • [2]. Raza S, et al. The cholesterol metabolite 27-hydroxycholesterol stimulates cell proliferation via ERβ in prostate cancer cells. Cancer Cell Int. 2017 May 11;17:52.
  • [3]. Kimbung S, et al. Impact of 27-hydroxylase (CYP27A1) and 27-hydroxycholesterol in breast cancer. Endocr Relat Cancer. 2017 Jul;24(7):339-349.
  • [4]. Fu X, et al. 27-hydroxycholesterol is an endogenous ligand for liver X receptor in cholesterol-loaded cells. J Biol Chem. 2001 Oct 19;276(42):38378-87.
  • [1]. DuSell CD, et al. 27-hydroxycholesterol is an endogenous selective estrogen receptor modulator. Mol Endocrinol. 2008 Jan;22(1):65-77.
  • [1]. DuSell CD, et al. 27-hydroxycholesterol is an endogenous selective estrogen receptor modulator. Mol Endocrinol. 2008 Jan;22(1):65-77.
  • [2]. Raza S, et al. The cholesterol metabolite 27-hydroxycholesterol stimulates cell proliferation via ERβ in prostate cancer cells. Cancer Cell Int. 2017 May 11;17:52.
  • [3]. Kimbung S, et

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