8-Benzyl-2-(4-Hydroxybenzyl)-6-(4-Hydroxyphenyl)Imidazo[1,2-A]Pyrazin-3(7H)-One 8-苄基-2-(4-羟基苄基)-6-(4-羟基苯基)咪唑并[1,2-a]吡嗪-3(7H)-酮

CAS 55779-48-1 MFCD00467176

化学结构图

55779-48-1
SMILES: OC1C=CC(CC2=NC3=C(CC4C=CC=CC=4)NC(=CN3C2=O)C2C=CC(O)=CC=2)=CC=1

化学属性

Mol. FormulaC26H21N3O3
Mol. Weight423

别名和识别编码

Chemical Name8-Benzyl-2-(4-Hydroxybenzyl)-6-(4-Hydroxyphenyl)Imidazo[1,2-A]Pyrazin-3(7H)-One
CAS Number55779-48-1
Synonym 3,2-Dihydro-2-(p-hydroxybenzyl)-6-(p-hydroxyphenyl)-8-benzylimidazolo[1,2-a]pyrazin-3-one 3,2-Dihydro-2-(p-hydroxybenzyl)-6-(p-hydroxyphenyl)-8-benzylimidazolo[1,2-a]pyrazin-3-one CLZN CLZN
MDL NumberMFCD00467176
PubChem Substance ID24892477
Chemical Name Translation8-苄基-2-(4-羟基苄基)-6-(4-羟基苯基)咪唑并[1,2-a]吡嗪-3(7H)-酮
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分类

  • {SNA} Calcium Probes, Calcium Signaling Research Tools, Coelenterazine, native, Fluorescent Labels, Intracellular Calcium Signaling, Luminescent, Other Fluorescent Labels, 生化试剂, 细胞信号转导和神经科学, 细胞生物学, 荧光探针,标记,粒子和染色剂
  • Fluorescent Labels & Indicators
  • {SA} Bioactive Small Molecules,

产品应用

  • A luminophore of the aequorin complex which is oxidized by oxygen to illuminate at 465nm when Ca2+ binds to the complex. Used to measure Ca2+ concentration in cells with high sensitivity an dlarge dy

相关文献及参考

  • Fluck, R.A., et al.: J. Cell Biol., 115, 1259 (1991),
  • Jones, K., et al.: Trends Biotechnol., 17, 477 (1999),
  • Fluck, R.A., et al., Slow calcium waves accompany cytokinesis in medaka fish eggs. J. Cell Biol. 115 , 1259-1265, (1991) 摘要
  • Jones, K., et al., Glowing jellyfish, luminescence and a molecule called coelenterazine. Trends Biotechnol. 17 , 477-481, (1999) 摘要
  • Dubuisson, M.L., et al., Antioxidative properties of natural coelenterazine and synthetic methyl coelenterazine in rat hepatocytes subjected to tert-butyl hydroperoxide-induced oxidative stress. Biochem. Pharmacol. 60 , 471-478, (2000) 摘要

安全信息

Hazard statements
  • H413 Maycauselonglastingharmfuleffectstoaquaticlife 可能对水生生物造成长期持续有害影响。
WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
GHS Symbol
Safety Statements
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触;
Precautionary statements
  • P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛,皮肤或衣服。

系列性分类


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