BVT-948 化合物BVT948

CAS 39674-97-0 MFCD00616487

化学结构图

39674-97-0
SMILES: CC1(C)C2=C(O)C(=O)C3C=CC=CC=3C2=NC1=O

化学属性

Mol. FormulaC14H11NO3
Mol. Weight241.24

别名和识别编码

Chemical NameBVT-948
Synonym 4-Hydroxy-3,3-dimethyl-2H-benzo[g]indole-2,5(3H)-dione
MDL NumberMFCD00616487
PubChem Substance ID24724422
CAS Number39674-97-0
Chemical Name Translation化合物BVT948
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分类

  • B, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Kinase/Phosphatase Biology, Tyrosine Phosphatase (TP), Tyrosine Phosphatase Biology, Tyros
  • {SNA} B, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Kinase/Phosphatase Biology, Tyrosine Phosphatase (TP), Tyrosine Phosphatase Biology, Tyrosine Phosphatase Inhibitors
  • {SNA} B, Bioactive Small Molecule Alphabetical Index, Kinase/Phosphatase Biology, Tyrosine Phosphatase (TP), Tyrosine Phosphatase Biology, Tyrosine Phosphatase Inhibitors, 生物活性小分子, 细胞信号转导和神经科学,

相关文献及参考

  • [2]. Blum G, et al. Small-molecule inhibitors of SETD8 with cellular activity. ACS Chem Biol. 2014 Nov 21;9(11):2471-8.
  • [3]. Hwang BM, et al. Protein tyrosine phosphatase controls breast cancer invasion through the expression of matrix metalloproteinase-9. BMB Rep. 2013 Nov;46(11):533-8.
  • Liljebris, C., et al., Oxidation of Protein Tyrosine Phosphatases as a Pharmaceutical Mechanism of Action: A Study Using 4-Hydroxy-3,3-dimethyl-2H-benzo[g]indole-2,5(3H)-dione. J. Pharmacol. Exp. Ther. 309 , 711-719, (2004)
  • [1]. Liljebris C, et al. Oxidation of protein tyrosine phosphatases as a pharmaceutical mechanism of action: a study using 4-hydroxy-3,3-dimethyl-2H-benzo[g]indole-2,5(3H)-dione. J Pharmacol Exp Ther. 2004 May;309(2):711
  • [1]. Liljebris C, et al. Oxidation of protein tyrosine phosphatases as a pharmaceutical mechanism of action: a study using 4-hydroxy-3,3-dimethyl-2H-benzo[g]indole-2,5(3H)-dione. J Pharmacol Exp Ther. 2004 May;309(2):711-9.

安全信息

GHS Symbol
Precautionary statements
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
Signal word Warning
Hazard statements
  • H317 May cause an allergic skin reaction 可能导致皮肤过敏
Hazard Codes Xi
WGK Germany3
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Safety Statements
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
Risk Statements
  • R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Kinase/Phosphatase Biology - Cell Signaling and Neuroscience
  5. Tyrosine Phosphatase Biology - Kinase/Phosphatase Biology
  6. Tyrosine Phosphatase Inhibitors - Tyrosine Phosphatase Biology
  7. Tyrosine Phosphatase (TP) - Tyrosine Phosphatase Inhibitors
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Kinase/Phosphatase Biology - Cell Signaling and Neuroscience
  5. Tyrosine Phosphatase Biology - Kinase/Phosphatase Biology
  6. Tyrosine Phosphatase Inhibitors - Tyrosine Phosphatase Biology
  7. Tyrosine Phosphatase (TP) - Tyrosine Phosphatase Inhibitors
  1. Medical Research Areas
  2. Metabolism
  3. Phosphatase  (磷酸酶)
  1. Medical Research Areas
  2. Metabolism
  3. Cytochrome P450  (细胞色素P450)

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