N-Cyclohexyl-N-Methyl-4-((2-Oxo-1,2-Dihydroquinolin-6-Yl)Oxy)Butanamide N-环己基-N-甲基-4-((2-氧代-1,2-二氢喹啉-6-基)氧基)丁酰胺

CAS 68550-75-4 MFCD00673958

化学结构图

68550-75-4
SMILES: CN(C1CCCCC1)C(=O)CCCOC1=CC2C=CC(=O)NC=2C=C1

化学属性

Mol. FormulaC20H26N2O3
Mol. Weight342.43
TSCANo

别名和识别编码

Chemical NameN-Cyclohexyl-N-Methyl-4-((2-Oxo-1,2-Dihydroquinolin-6-Yl)Oxy)Butanamide
Synonym 6-[3-(N-Cyclohexyl-N-methylcarbamoyl)propoxy]quinolin-2[1H]-one 6-[3-(N-Cyclohexyl-N-methylcarbamoyl)propoxy]quinolin-2[1H]-one OPC 3689 OPC 3689
MDL NumberMFCD00673958
PubChem Substance ID24278337
CAS Number68550-75-4
Chemical Name TranslationN-环己基-N-甲基-4-((2-氧代-1,2-二氢喹啉-6-基)氧基)丁酰胺
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分类

  • {SNA} Cyclic Nucleotide Metabolism, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, G Proteins and Cyclic Nucleotides, P to Q, Phosphodiesterase III, Phosphodiesterase Inhibitors, 生化试剂, 细胞信号转导和神经科学, 细胞生物学, 酶、抑制剂和底物
  • {SNA} Bioactive Small Molecules, Biochemicals and Reagents, CI-CY, Cell Biology, Cell Signaling and Neuroscience, Cyclic Nucleotide Metabolism, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, G Proteins and Cyclic Nucleotides,
  • {SA} Bioactive Small Molecules, Biochemicals and Reagents, CI-CY, Cell B

相关文献及参考

  • 1. Hayashi, H., and Sudo, T., Effects of the cAMP-elevating agents cilostamide, cilostazol and forskolin on the phosphorylation of Akt and GSK-3beta in platelets Thromb. Haemost. 102 , 327-335, (2009) 摘要
  • Tang, K.M., et al. Eur. J. Pharmacol. 268 , 105, (1994) 摘要
  • Verghase, M.W., et al. J. Pharmacol. Exp. Ther. 272 , 1313, (1995) 摘要
  • [1]. Sudo T, et al. Potent effects of novel anti-platelet aggregatory cilostamide analogues on recombinant cyclic nucleotide phosphodiesterase isozyme activity. Biochem Pharmacol. 2000 Feb 15;59(4):347-56.

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

系列性分类

  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Enzyme Inhibitors - Enzymes, Inhibitors, and Substrates
  5. Enzyme Inhibitors by Enzyme - Enzyme Inhibitors
  6. P to Q - Enzyme Inhibitors by Enzyme
  7. Phosphodiesterase III - P to Q
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. G Proteins and Cyclic Nucleotides - Cell Signaling and Neuroscience
  5. Cyclic Nucleotide Metabolism - G Proteins and Cyclic Nucleotides
  6. Phosphodiesterase Inhibitors - Cyclic Nucleotide Metabolism
  1. Medical Research Areas
  2. Metabolism
  3. Phosphodiesterase (PDE)  (磷酸二酯酶)

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