8-(4-Chlorophenylthio)-guanosine 3',5'-cyclic monophosphate sodium salt

CAS 51239-26-0 MFCD00674888

化学结构图

51239-26-0
SMILES: [Na+].NC1NC(=O)C2N=C(SC3C=CC(Cl)=CC=3)N([C@@H]3O[C@@H]4COP([O-])(=O)O[C@H]4[C@H]3O)C=2N=1

化学属性

Mol. FormulaC16H14ClN5NaO7PS
Mol. Weight509.79

别名和识别编码

Chemical Name8-(4-Chlorophenylthio)-guanosine 3',5'-cyclic monophosphate sodium salt
Synonym 8-(4-Chlorophenylthio)-guanosine 3',5'-cyclic monophosphate sodium salt 8-pCPT-cGMP 8-pCPT-cGMP pCPT-cGMP pCPT-cGMP
MDL NumberMFCD00674888
PubChem Substance ID24892786
CAS Number51239-26-0
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分类

  • Bioactive Small Molecules, C-CH, Cell Biology, Cell Signaling and Neuroscience, Cyclic Nucleotide Metabolism, Cyclic Nucleotides and Analogs, G Proteins and Cyclic Nucleotides, Kinase/Phosphatase Biology, Protein Kinase G (PKG), Serine/Threonine Kinase Activators, Serine/Threonine Kinase Biology
  • {SNA} Bioactive Small Molecule Alphabetical Index, C-CH, Cyclic Nucleotide Metabolism, Cyclic Nucleotides and Analogs, G Proteins and Cyclic Nucleotides, Kinase/Phosphatase Biology, Protein Kinase G (PKG), Serine/Threonine Kinase Activators, Serine/Threonine Kinase Biology, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
  • {SNA} Bioactive Sm

相关文献及参考

  • VanUffelen, B.E., et al., Interaction of cyclic GMP and cyclic AMP during neutrophil migration: involvement of phosphodiesterase type III. Biochem. Pharmacol. 56 , 1061-1063, (1998) 摘要
  • Wei, J.Y., et al., Substituted cGMP analogs can act as selective agonists of the rod photoreceptor cGMP-gated cation channel. J. Mol. Neurosci. 10 , 53-64, (1998) 摘要
  • He, P., et al., cGMP modulates basal and activated microvessel permeability independently of [Ca 2+ ]i. Am. J. Physiol. 274(6 Pt 2) , H1865-H1874, (1998)
  • Hood, J., and Granger, H.J., Protein kinase G mediates vascular endothelial growth factor-induced Raf-1 activation and proliferation in human endothelial cells. J. Biol. Chem. 273 , 23504-23508, (1998) 摘要
  • Suhasini, M., et al., Cyclic-GMP-dependent protein kinase inhibits the ras/mitogen-activated protein kinase pathway. Mol. Cell. Biol. 18 , 6983-6994, (1998) 摘要

安全信息

WGK Germany3

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. G Proteins and Cyclic Nucleotides - Cell Signaling and Neuroscience
  5. Cyclic Nucleotide Metabolism - G Proteins and Cyclic Nucleotides
  6. Cyclic Nucleotides and Analogs - Cyclic Nucleotide Metabolism
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. G Proteins and Cyclic Nucleotides - Cell Signaling and Neuroscience
  5. Cyclic Nucleotide Metabolism - G Proteins and Cyclic Nucleotides
  6. Cyclic Nucleotides and Analogs - Cyclic Nucleotide Metabolism
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Kinase/Phosphatase Biology - Cell Signaling and Neuroscience
  5. Serine/Threonine Kinase Biology - Kinase/Phosphatase Biology
  6. Serine/Threonine Kinase Activators - Serine/Threonine Kinase Biology
  7. Protein Kinase G (PKG) - Serine/Threonine Kinase Activators

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