CA-074 Methyl Ester CA-074 甲酯

CAS 147859-80-1 MFCD00797532

化学结构图

147859-80-1
SMILES: C[C@@H](CC)[C@H](NC(=O)[C@H]1O[C@@H]1C(=O)NCCC)C(=O)N1CCC[C@H]1C(=O)OC

化学属性

Mol. FormulaC19H31N3O6
Mol. Weight397.469

别名和识别编码

Chemical NameCA-074 Methyl Ester
Chemical Name TranslationCA-074 甲酯
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相关文献及参考

  • [2]. Patel N, et al. CA-074Me compound inhibits osteoclastogenesis via suppression of the NFATc1 and c-FOS signaling pathways. J Orthop Res. 2015 Oct;33(10):1474-86
  • [3]. Zhang L, et al. Treatment with CA-074Me, a Cathepsin B inhibitor, reduces lung interstitial inflammation and fibrosis in a rat model of polymyositis. Lab Invest. 2015 Jan;95(1):65-77
  • [1]. Xu Y, et al. Protective mechanisms of CA074-me (other than cathepsin-B inhibition) against programmed necrosis induced by global cerebral ischemia/reperfusion injury in rats. Brain Res Bull. 2016 Jan;120:97-105
  • [1]. Xu Y, et al. Protective mechanisms of CA074-me (other than cathepsin-B inhibition) against programmed necrosis induced by global cerebral ischemia/reperfusion injury in rats. Brain Res Bull. 2016 Jan;120:97-105
  • [2]. Patel N, et al. CA-074Me compound inhibits osteoclastogenesis via suppression of the NFATc1 and c-FOS signaling pathways. J Orthop Res. 2015 Oct;33(10):1474-86

系列性分类

  1. Medical Research Areas
  2. Metabolism
  3. Cathepsin  (组织蛋白酶)

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