Astressin
CAS 170809-51-5 MFCD00798715
化学结构图
SMILES: C[C@@H](CC)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCC)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H]1CCCCNC(=O)CC[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC2=CNC=N2)NC(=O)[C@H](N)CC2C=CC=CC=2)C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC2=CNC=N2)C(=O)N1)[C@@H](C)CC)C(N)=O
化学属性
| Mol. Formula | C161H269N49O42 |
|---|---|
| Mol. Weight | 3563.16 |
别名和识别编码
| Chemical Name | Astressin |
|---|---|
| Synonym | [D-Phe12, Nle21,38, Glu30, Lys33]-Corticotropin Releasing Factor fragment 12-41 |
| MDL Number | MFCD00798715 |
| CAS Number | 170809-51-5 |
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分类
- {SNA} AN-AZ, Bioactive Small Molecules, CRF, Cell Biology, Cell Signaling and Neuroscience, Neuropeptides, Peptides and Proteins, Peptides for Cell Biology, Releasing Factors
- {SNA} CRF, Neuropeptides, Peptides and Proteins, Peptides for Cell Biology, Releasing Factors, 细胞信号转导和神经科学, 细胞生物学
- AN-AZ, Bioactive Small Molecules, CRF, Cell Biology, Cell Signaling and Neuroscience, Neuropeptides, Peptides and Proteins, Peptides for Cell Biology, Releasing Factors
相关文献及参考
- Gulyas, J., et al., Potent structurally constrained agonists and competitive antagonists of corticotropin-releasing factor. Proc. Natl. Acad. Sci. U. S. A. 92 , 10575, (1995) 摘要
- Ha, B.K., et al., Corticotropin releasing factor induces proliferation of cerebellar astrocytes. J. Neurosci. 62 , 789-798, (2000) 摘要
- Sajdyk, T.J., and Gehlert, D.R., Astressin, a corticotropin releasing factor antagonist, reverses the anxiogenic effects of urocortin when administered into the basolateral amygdala. Brain Res. 877 , 226-234, (2000) 摘要
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