Benzyl ((2S)-3-Methyl-1-Oxo-1-((1-Oxo-3-Phenylpropan-2-Yl)Amino)Butan-2-Yl)Carbamate ((2S)-3-甲基-1-氧代-1-((1-氧代-3-苯基丙-2-基)氨基)丁-2-基)氨基甲酸苄酯
CAS 88191-84-8 MFCD00798796
化学结构图
SMILES:
化学属性
| Mol. Formula | C22H26N2O4 |
|---|---|
| Mol. Weight | 382 |
别名和识别编码
| Chemical Name | Benzyl ((2S)-3-Methyl-1-Oxo-1-((1-Oxo-3-Phenylpropan-2-Yl)Amino)Butan-2-Yl)Carbamate |
|---|---|
| Synonym | Calpain Inhibitor III MDL 28170 |
| MDL Number | MFCD00798796 |
| PubChem Substance ID | 24278565 |
| Chemical Name Translation | ((2S)-3-甲基-1-氧代-1-((1-氧代-3-苯基丙-2-基)氨基)丁-2-基)氨基甲酸苄酯 |
| CAS Number | 88191-84-8 |
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分类
- {SNA} Aldehydes, Apoptosis Inhibitors, Apoptosis and Cell Cycle, Application Index, Bioactive Small Molecules, Biochemic
- {SNA} Aldehydes, Apoptosis Inhibitors, Apoptosis and Cell Cycle, Application Index, Bioactive Small Molecule Alphabetical Index, Building Blocks,
相关文献及参考
- [2]. Li PA, et al. Postischemic treatment with calpain inhibitor MDL 28170 ameliorates brain damage in a gerbil model of global ischemia. Neurosci Lett. 1998 May 8;247(1):17-20.
- [3]. Ai J, et al. Calpain inhibitor MDL-28170 reduces the functional and structural deterioration of corpus callosum following fluid percussion injury. J Neurotrauma. 2007 Jun;24(6):960-78.
- [4]. De Strooper B, et al. A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain. Nature. 1999 Apr 8;398(6727):518-22.
- [5]. Kharatmal SB, et al. Calpain inhibitor, MDL 28170 confer electrophysiological, nociceptive and biochemical improvement in diabetic neuropathy. Neuropharmacology. 2015 Oct;97:113-21.
- [1]. Chen ZF, et al. Neuronal recovery after moderate hypoxia is improved by
- [1]. Chen ZF, et al. Neuronal recovery after moderate hypoxia is improved by the calpain inhibitor MDL28170. Brain Res. 1997 Sep 19;769(1):188-92.
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