Cinalukast

CAS 128312-51-6 MFCD00864778

化学结构图

128312-51-6
SMILES: CCC(CC(=O)NC1C=C(/C=C/C2=NC(=CS2)C2CCC2)C=CC=1)(CC)C(O)=O

化学属性

Mol. FormulaC23H28N2O3S
Mol. Weight412.55

别名和识别编码

Chemical NameCinalukast
CAS Number128312-51-6
Synonym (E)-4-[[3-(2-(4-Cyclobutyl-2-thiazolyl)ethenyl)phenyl]amino]-2,2-diethyl-4-oxobutanoic acid Ro 24-5913 4-[[3-[(1E)-2-(4-Cyclobutyl-2-thiazolyl)ethenyl]phenyl]amino]-2,2-diethyl-4-oxo-Butanoic Acid Ro 24-5913
MDL NumberMFCD00864778
PubChem Substance ID24724447
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分类

  • {SNA} Approved Therapeutics/Drug Candidates, Arachidonic Acid Cascade, Bioactive Small Molecule Alphabetical Index, CI-CZ, Diversification Ready Pharma-Developed Compounds, Leukotrienes, Lipids in Cell Signaling, Roche, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
  • {SNA} Approved Therapeutics/Drug Candidates, Arachidonic Acid Cascade, Bioactive Small Molecules, CI-CY, Cell Biology, Cell Signaling and Neuroscience, Leukotrienes, Lipids in Cell Signaling, Roche
  • Approved Therapeutics/Drug Candidates, Arachidonic Acid Cascade, Bioactive Small Molecules, CI-CY, Cell Biology,

产品应用

  • A novel leukotriene D4 antagonist.

相关文献及参考

  • O'Donnell, M., et al.: J. Pharmacol. Exp. Ther., 259, 751 (1991),
  • Jones, T., et al.: J. Physiol. Pharmacol., 73, 191 (1995),
  • Kawano, T., et al.: J. Allergy Clin. Immunol., 112, 369 (2003),
  • Maehr, H. and Yang, R., A convergent synthesis of Ro24-5913, a novel leukotriene D 4 antagonist. Tetrahedron Lett. 37 , 5445-5448, (1996)

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Lipids in Cell Signaling - Cell Signaling and Neuroscience
  5. Arachidonic Acid Cascade - Lipids in Cell Signaling
  6. Leukotrienes - Arachidonic Acid Cascade

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