Rufinamide 卢非酰胺

CAS 106308-44-5 MFCD00865314

化学结构图

106308-44-5
SMILES: NC(=O)C1=CN(CC2C(F)=CC=CC=2F)N=N1

化学属性

Mol. FormulaC10H8F2N4O
Mol. Weight238
Melting Point239-243

别名和识别编码

Chemical NameRufinamide
CAS Number106308-44-5
Synonym 1-[(2,6-difluorophenyl)methyl]-1H-1,2,3-Triazole-4-carboxamide 1-​[(2,6-​difluorophenyl)​methyl]​-​1H-​1,2,3-​Triazole-​4-​carboxamide
MDL NumberMFCD00865314
PubChem Substance ID24724595
Beilstein Registry Number13495800
Chemical Name Translation卢非酰胺
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • Bases & Related Reagents
  • {SNA} Anticonvulsants, Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Eisai, Neurobiology, Neuroscience, Novartis, Pharmacologicals, R
  • Nucleotides
  • Heterocycles
  • Pharmaceuticals
  • {SNA} Anticonvulsants, Approved

产品应用

  • Antiepileptic triazole derivative which decreases firing by neurons at sodium channels. Anticonvulsant.

相关文献及参考

  • Cheung, W.K., et al.: Pharm. Res., 12, 1878 (1995),
  • Cardot, J.-M., et al.: Biopharm. Drug Dispos., 19, 259 (1998),
  • Palhagen, S., et al.: Epilepsy Res., 43, 115 (2001),

安全信息

WGK Germany3
GHS Symbol
UN Number 3077
Hazard Codes 9
Signal word Warning
Safety Statements
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后，立即用大量…（由生产厂家指定）冲洗；
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
Risk Statements
  • R28 Very toxic if swallowed 吞咽极毒
  • R38 Irritating to skin 刺激皮肤
  • R41 Risk of serious damage to eyes 有严重损伤眼睛的危险
  • R48 Danger of serious damage to health by prolonged exposure 长期接触有严重损害健康的危险
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P304+P340+P312
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Packing GroupIII

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Neuroscience - Cell Signaling and Neuroscience
  5. Neurobiology - Neuroscience
  6. Pharmacologicals - Neurobiology
  7. Anticonvulsants - Pharmacologicals

相关产品推荐