Acetamide, 2-((diphenylmethyl)sulfinyl)-N-hydroxy-

CAS 63547-13-7 MFCD00865357

化学结构图

63547-13-7
SMILES: ONC(=O)CS(=O)C(C1C=CC=CC=1)C1C=CC=CC=1

化学属性

Mol. FormulaC15H15NO3S
Mol. Weight289.37

别名和识别编码

Chemical NameAcetamide, 2-((diphenylmethyl)sulfinyl)-N-hydroxy-
CAS Number63547-13-7
Synonym 2-(Benzhydrylsulfinyl)acetohydroxamic Acid Acetohydroxamic acid, 2-((diphenylmethyl)sulfinyl)- 2-((Diphenylmethyl)sulfinyl)-N-hydroxyacetamide 2-[(Diphenylmethyl)sulfinyl]-N-hydroxyacetamide Adrafinil Olmifon CRL 40028 2-(Benzhydrylsulfinyl)acetohydroxamic acid
MDL NumberMFCD00865357
PubChem Substance ID24890429
EC Number264-303-1
Beilstein Registry Number1990030
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分类

  • Aromatics
  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • Sulfur & Selenium Compounds,
  • {SNA} A-AM, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Neurobiology, Neuroscience, Pharmacologicals, Stimulants

产品应用

  • ?-Adrenergic agonist. Treatment of depression.

相关文献及参考

  • Duteil, J., et al.: Eur. J. Pharmacol., 59, 121 (1979),
  • Roze, C., et al.: Arch. Int. Pharmacodyn. Ther., 265, 119 (1983),
  • Rambert, F.A., et al.: J. Pharmacol., 17, 37 (1986),

安全信息

GHS Symbol
Hazard statements
  • H302 Harmful if swallowed 吞食有害
WGK Germany3
Signal word Warning
RTECSAB8139500
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes Xn
Risk Statements
  • R22 Harmful if swallowed 吞咽有害
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 859 mg/kg
TOXIC EFFECTS :
   Behavioral - excitement
REFERENCE :
   JNPHAG Journal de Pharmacologie.  (SPPIF, B.P.22, F-41353 Vineuil, France)
   V.1-    1970-  Volume(issue)/page/year: 17,37,1986

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1950 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #4066686

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Bioactive Small Molecules - Cell Biology
  4. A-AM - Bioactive Small Molecules
  1. Functional Group 官能团索引
  2. sulfoxide
  1. Functional Group 官能团索引
  2. hydroxamic acid

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