Pyrrolidine,1-(2-(4-(1-(4-iodophenyl)-2-phenyl-1-butenyl)phenoxy)ethyl)-, (E)-

CAS 116057-75-1 MFCD00865557

化学结构图

116057-75-1
SMILES: CC/C(=C(\C1C=CC(I)=CC=1)/C1C=CC(=CC=1)OCCN1CCCC1)/C1C=CC=CC=1

化学属性

Mol. FormulaC28H30INO
Mol. Weight523.44837

别名和识别编码

Chemical NameIdoxifene
Synonym CB 7432 (E)-1-(2-(4-(1-(4-Iodophenyl)-2-phenyl-1-butenyl)phenoxy)ethyl)pyrrolidine Iodoxifene SB 223030
CAS Number116057-75-1
Chemical Name Translation
FormulaC28H30INO
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

产品应用

  • Idoxifene is a non-steroidal estrogen antagonist. It is also structurally analogous to tamoxifen. Idoxifene was both active and well tolerated in postmenopausal women with metastatic breast cancer. Idoxifene had similar efficacy and toxicity to tamoxifen in this randomized comparison. (source: Ann Oncol. 2003 Feb;14(2):233-41).

安全信息

RTECSUY1328700 
TYPE OF TEST            : Sex chromosome loss and nondisjunction
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - rat
DOSE/DURATION           : 35 mg/kg
REFERENCE :
   CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
   Southfield Road, Eynsham, Oxford OX8 1JJ, UK)  V.1-    1980-
   Volume(issue)/page/year: 17,1051,1996

系列性分类

  1. Medical Research Areas
  2. Endocrinology & Hormones
  3. Estrogen/progestogen Receptor

相关产品推荐