西拉普利 西拉普利

CAS 88768-40-5 MFCD00865788

化学结构图

88768-40-5
SMILES: CCOC(=O)[C@H](CCC1C=CC=CC=1)N[C@H]1CCCN2CCC[C@@H](C(O)=O)N2C1=O

化学属性

Mol. FormulaC22H31N3O5
Mol. Weight417.5

别名和识别编码

Chemical NameCilazapril
CAS Number88768-40-5
Synonym (1S,9S)-
Chemical Name Translation西拉普利
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分类

  • Chiral Reagents
  • Pharmaceuticals
  • Intermediates & Fine Chemicals,

产品应用

  • An ACE inhibitor. Hydrolyzed in vivo to the active diacid metabolite (Cilazaprilat). Antihypertensive.

相关文献及参考

  • [2]. Nussberger, J., et al., Repeated administration of the converting enzyme inhibitor cilazapril to normal volunteers. J Cardiovasc Pharmacol, 1987. 9(1): p. 39-44.
  • Natoff, I.L., et al.: J. Cardiovasc. Pharmacol., 7, 569 (1985),
  • Pordy, R.C., et al.: Cardiology, 86, 41 (1995),
  • Szucs, T., et al.: Drugs, 41, Suppl.1, 18 (1991),
  • [1]. Szucs, T., Cilazapril. A review. Drugs, 1991. 41 Suppl 1: p. 18-24.
  • [1]. Szucs, T., Cilazapril. A review. Drugs, 1991. 41 Suppl 1: p. 18-24.
  • [2]. Nussberger, J., et al., Repeated administration of the converting enzyme inhibitor cilazapril to normal volunteers. J Cardiovasc Pharmacol, 1987. 9(1): p. 39-44.

系列性分类


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