Fasudil 法舒地尔

CAS 103745-39-7 MFCD00866182

化学结构图

103745-39-7
SMILES: Cl.Cl.O=S(=O)(C1C=CC=C2C=NC=CC2=1)N1CCCNCC1

化学属性

Mol. FormulaC14H17N3O2S
Mol. Weight327.83
TSCANo

别名和识别编码

Chemical NameFasudil
MDL NumberMFCD00866182
Synonym HA-1077
CAS Number103745-39-7
Merck Number14,3942
Chemical Name Translation法舒地尔
LabNetwork Molecule IDLN01292748
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相关文献及参考

  • [2]. Huang XN, et al. The effects of fasudil on the permeability of the rat blood-brain barrier and blood-spinal cordbarrier following experimental autoimmune encephalomyelitis. J Neuroimmunol. 2011 Oct 28;239(1-2):61-7.
  • [3]. Uehata M, et al. Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension. Nature. 1997 Oct 30;389(6654):990-4.
  • [4]. Fukushima M, et al. Fasudil hydrochloride hydrate, a Rho-kinase (ROCK) inhibitor, suppresses collagen production and enhances collagenase activity in hepatic stellate cells. Liver Int. 2005 Aug;25(4):829-38.
  • [5]. Corbin KD, et al. Choline metabolism provides novel insights into nonalcoholic fatty liver disease and its progression. Curr Opin Gastroenterol. 2012 Mar;28(2):159-65.
  • [6]. Zhang J, et al. Inhibition of the activity of Rho-kinase reduces cardiomyocyte apoptosis in heart ischemia/reperfusion via suppressing JNK-mediated AIF translocation. Clin Chim Acta

安全信息

GHS Symbol
WGK Germany3
RTECSHM4031166

系列性分类


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