Iloperidone 伊潘立酮
CAS 133454-47-4 MFCD00866688
化学结构图
SMILES: CC(=O)C1=CC(OC)=C(C=C1)OCCCN1CCC(CC1)C1=NOC2C=C(F)C=CC=21
化学属性
| Mol. Formula | C24H27FN2O4 |
|---|---|
| Mol. Weight | 426.49 |
| Melting Point | 122.0 to 126.0 deg-C |
别名和识别编码
| Chemical Name | Iloperidone |
|---|---|
| CAS Number | 133454-47-4 |
| Synonym | 1-[4-[3-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]propoxy]-3-methoxyphenyl]ethanone 1-[4-[3-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]propoxy]-3-methoxyphenyl]ethanone, HP 873 |
| Chemical Name Translation | 伊潘立酮 |
| MDL Number | MFCD00866688 |
| Reaxys-RN | 7233425 |
| Merck Number | 4900 |
| PubChem Substance ID | 253662251 |
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信息真实价格透明
资金保障
专业采购外包团队在线服务
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分类
- Aromatics
- Heterocycles
- Pharmaceuticals
- Intermediates & Fine Chemicals
产品应用
- Combined dopamine (D2) and serotonin (5HT2) receptor antagonist. Antipsychotic.
相关文献及参考
- [2]. Sainati, S.M., et al., Safety, tolerability, and effect of food on the pharmacokinetics of iloperidone (HP 873), a potential atypical antipsychotic. J Clin Pharmacol, 1995. 35(7): p. 713-20.
- [3]. Albers, L.J., A. Musenga, and M.A. Raggi, Iloperidone: a new benzisoxazole atypical antipsychotic drug. Is it novel enough to impact the crowded atypical antipsychotic market? Expert Opin Investig Drugs, 2008. 17(1): p. 61-75.
- Kongsamut, S., et al.: Eur. J. Pharmacol., 317, 417 (1996),
- Sainati, S.M., et al.: J. Clin. Pharmacol., 35, 713 (1995),
- Szewczak, M.R., et al.: J. Pharmacol. Exp. Ther., 274, 1404 (1995),
- [1]. Kongsamut, S., et al., Iloperidone binding to human and rat dopamine and 5-HT receptors. Eur J Pharmacol, 1996. 317(2-3): p. 417-23.
- [1]. Kongsamut, S., et al., Iloperidone binding to human and rat dopamine and 5-HT receptors. Eur J Pharmacol, 1996. 317(2-3): p. 417-23.
- [2]. Sainati, S.M., et al., Safety, tolerabi
安全信息
GHS Symbol
- S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
- P201 Obtain special instructions before use. 使用前获取专门指示。
- P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前，切勿操作。
- P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛，皮肤或衣服。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P308+P313
- P405 Store locked up. 上锁保管。
- P501 Dispose of contents/container to..… 处理内容物/容器.....
- H361 Suspected of damaging fertility or the unborn child 怀疑对生育能力或未出生婴儿造成伤害
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