Drospirenone 屈螺酮

CAS 67392-87-4 MFCD00867350

化学结构图

67392-87-4
SMILES: C[C@]12CC[C@H]3[C@H]([C@@H]1[C@@H]1C[C@@H]1[C@]12CCC(=O)O1)[C@H]1C[C@H]1C1=CC(=O)CC[C@@]13C

化学属性

Mol. FormulaC24H30O3
Mol. Weight366
Melting Point199.0 to 203.0 deg-C

别名和识别编码

Chemical NameDrospirenone
Synonym 6β,7β,15β,16β -Dimethylene-3-oxo-17α-pregn-4-ene-21,17-carbolactone 6β,7β,15β,16β -Dimethylene-3-oxo-17α-pregn-4-ene-21,17-carbolactone Dihydrospirorenone 6β,7β:15β,16β -Dimethylene-3-oxo-17α-pregn-4-ene-21,17-carbolactone 6β,7β:15β,16β -Dimethylene-3-oxo-17α-pregn-4-ene-21,17-carbolactone Dihydrospirorenone Dihydrospirorenone
MDL NumberMFCD00867350
CAS Number67392-87-4
EC Number266-679-2
PubChem Substance ID172089115
LabNetwork Molecule IDLN01290259
Chemical Name Translation屈螺酮
Reaxys-RN4765500
Merck Number3454
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分类

  • {SNA} Approved Therapeutics/Drug Candidates, Bayer, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Cytokines, Growth Factors and Hormones, DIG-DY, Hormones, Progesterone, Steroid Hormones
  • Approved Therapeutics/Drug Candidates, Bayer, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience
  • {SNA} Approved Therapeutics/Drug Candidates, Bayer, Bioactive Small Molecule Alphabetical Index, Cytokines, Growth Factors and Hormones, DIG-DY, Hormones, Progesterone, Steroid Hormones, 生物活性小分子, 细胞信号转导和神经科学,

相关文献及参考

  • Jick SS, Hernandez RK., Risk of non-fatal venous thromboembolism in women using oral contraceptives containing drospirenone compared with women using oral contraceptives containing levonorgestrel: case-control study using United States claims data. Br. Med. J. 343 , d2151, (2011)
  • Tang M, Naidu D, Hearing P, Handwerger S, Tabibzadeh S., LEFTY, a member of the transforming growth factor-beta superfamily, inhibits uterine stromal cell differentiation: a novel autocrine role. Endocrinology 151 , 1320-1330, (2010)
  • Africander D, Verhoog N, Hapgood JP, Molecular mechanisms of steroid receptor-mediated actions by synthetic progestins used in HRT and contraception. Steroids 76 , 636-652, (2011)

安全信息

GHS Symbol
Precautionary statements
  • P308+P313
  • P201 Obtain special instructions before use. 使用前获取专门指示。
Signal word Danger
Hazard statements
  • H360 May damage fertility or the unborn child 可能对生育能力或未出生婴儿造成伤害
WGK Germany3
RTECSWH1299000
Safety Statements
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
Hazard Codes T
Risk Statements
  • R60 May impair fertility 可能降低生殖能力
Storage condition 0-10°C

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Cytokines, Growth Factors and Hormones - Cell Signaling and Neuroscience
  5. Hormones - Cytokines, Growth Factors and Hormones
  6. Steroid Hormones - Hormones
  7. Progesterone - Steroid Hormones

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