(S)-N-((6S,9S,12R,15S,18S,21S,24S)-21-((1H-Indol-3-yl)methyl)-1-amino-12-(tert-butoxymethyl)-6-((S)-2-(2-carbamoylhydrazine-1-carbonyl)pyrrolidine-1-carbonyl)-15-(4-hydroxybenzyl)-18-(hydroxymethyl)-25-(1H-imidazol-5-yl)-1-imino-9-isobutyl-8,11,14,17,20,23-hexaoxo-2,7,10,13,16,19,22-heptaazapentacosan-24-yl)-5-oxopyrrolidine-2-carboxamide acetate (S)-N-((6S,9S,12R,15S,18S,21S,24S)-21-((1H-吲哚-3-基)甲基)-1-氨基-12-(叔丁氧基甲基)-6-((S)-2-(2-氨基甲酰肼-1-羰基)吡咯烷-1-羰基)-15-(4-羟基苄基)-18-(羟甲基)-25-(1H-咪唑-5-基)-1-亚氨基-9-异丁基-8,11,14,17,20,23-六氧代-2,7,10,13,16,19,22-七氮杂二十五碳-24-基)-5-氧代吡咯烷-2-甲酰胺乙酸盐

CAS 145781-92-6 MFCD00867894

化学结构图

145781-92-6
SMILES: CC(C)C[C@H](NC(=O)[C@@H](COC(C)(C)C)NC(=O)[C@H](CC1=CC=C(O)C=C1)NC(=O)[C@H](CO)NC(=O)[C@H](CC1=CNC2C=CC=CC1=2)NC(=O)[C@H](CC1=CNC=N1)NC(=O)[C@@H]1CCC(=O)N1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)NNC(N)=O

化学属性

Mol. FormulaC59H84N18O14
Mol. Weight1269.42

别名和识别编码

Chemical Name(S)-N-((6S,9S,12R,15S,18S,21S,24S)-21-((1H-Indol-3-yl)methyl)-1-amino-12-(tert-butoxymethyl)-6-((S)-2-(2-carbamoylhydrazine-1-carbonyl)pyrrolidine-1-carbonyl)-15-(4-hydroxybenzyl)-18-(hydroxymethyl)-25-(1H-imidazol-5-yl)-1-imino-9-isobutyl-8,11,14,17,20,23-hexaoxo-2,7,10,13,16,19,22-heptaazapentacosan-24-yl)-5-oxopyrrolidine-2-carboxamide acetate
Chemical Name Translation(S)-N-((6S,9S,12R,15S,18S,21S,24S)-21-((1H-吲哚-3-基)甲基)-1-氨基-12-(叔丁氧基甲基)-6-((S)-2-(2-氨基甲酰肼-1-羰基)吡咯烷-1-羰基)-15-(4-羟基苄基)-18-(羟甲基)-25-(1H-咪唑-5-基)-1-亚氨基-9-异丁基-8,11,14,17,20,23-六氧代-2,7,10,13,16,19,22-七氮杂二十五碳-24-基)-5-氧代吡咯烷-2-甲酰胺乙酸盐
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相关文献及参考

  • [2]. Halle C F Moore, et al. Goserelin for ovarian protection during breast-cancer adjuvant chemotherapy. N Engl J Med. 2015 Mar 5;372(10):923-32.
  • [1]. Ning Zhang, et al. Goserelin promotes the apoptosis of epithelial ovarian cancer cells by upregulating forkhead box O1 through the PI3K/AKT signaling pathway. Oncol Rep. 2018 Mar; 39(3): 1034–1042.
  • [1]. Ning Zhang, et al. Goserelin promotes the apoptosis of epithelial ovarian cancer cells by upregulating forkhead box O1 through the PI3K/AKT signaling pathway. Oncol Rep. 2018 Mar; 39(3): 1034–1042.
  • [2]. Halle C F Moore, et al. Goserelin for ovarian protection during breast-cancer adjuvant chemotherapy. N Engl J Med. 2015 Mar 5;372(10):923-32.

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Cytokines, Growth Factors and Hormones - Cell Signaling and Neuroscience
  5. Hormones - Cytokines, Growth Factors and Hormones
  6. Other Protein/Peptide Hormones - Hormones
  7. Goserelin - Other Protein/Peptide Hormones
  1. Medical Research Areas
  2. GPCR & G Protein
  3. GnRH Receptor  (促性腺激素释放激素受体)

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