芍药甙芍药苷 芍药苷

CAS 23180-57-6 MFCD00869331

化学结构图

23180-57-6
SMILES: C[C@@]12C[C@@]3(O)O[C@@H](O1)[C@]1(COC(=O)C4C=CC=CC=4)[C@H]3C[C@@]12O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

化学属性

Mol. FormulaC23H28O11
Mol. Weight480.47
Density1.63

别名和识别编码

Chemical Name芍药甙芍药苷
CAS Number23180-57-6
EC Number245-476-2
Synonym Peoniflorin 芍药甙 5beta-[(Benzoyloxy)methyl]tetrahydro-5-hydroxy-2-methyl-2,5-methano-1H-3,4-dioxacyclobuta[cd]pentalen-1alpha(2H)-yl-beta-D-glucopyranoside
MDL NumberMFCD00869331
Beilstein Registry Number2384789
Reaxys-RN6079909
PubChem Substance ID125307355
Chemical Name Translation芍药苷
信息真实价格透明    资金保障    专业采购外包团队在线服务   
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分类

  • {SNA} Biochemicals and Reagents, Carbohydrates, Carbohydrates A to Z, Carbohydrates P-Z, Cell Biology, Nutrition Research, Phytochemicals by Chemical Classification, Terpenes and Terpenoids (Isoprenoids)
  • {SNA} Carbohydrates A to Z, Carbohydrates P-Z, Phytochemicals by Chemical Classification, Terpenes and Terpenoids (Isoprenoids), 生化试剂, 碳水化合物, 细胞生物学, 营养研究
  • {SNA} Biochemicals and Reagents, Carbohydrates, Carbohydrates A to Z, Carbohydrates P-Z, Nutrition Research, Phytochemicals by Chemical Classification, Terpenes and Terpenoids (Isoprenoids)

产品应用

  • 中药成分来自芍药的根。中药上其解痉止痛的属性。抗心肌缺血、具抗凝抑制血小板聚集作用；解痉作用；镇痛、镇静作用；抗炎、抗溃疡作用；保肝作用；调节免疫力作用和抗高血糖作用；耐缺氧作用等。
  • 临床应用：用于冠心病的治疗；用于老年性疾病，增强体质与免疫功能、抗炎止咳、祛痰平喘等方面，尤其是老年慢性呼吸道疾病的治疗中可作辅助药物。

相关文献及参考

  • [2]. Cao BY, et al. Paeoniflorin, a potent natural compound, protects PC12 cells from MPP+ and acidic damage via autophagic pathway. J Ethnopharmacol. 2010;131(1):122-129.
  • [3]. Yan D, et al. Paeoniflorin, a novel heat shock protein-inducing compound. Cell Stress Chaperones. 2004;9(4):378-389.
  • [1]. Xiang Y, et al. Paeoniflorin: a monoterpene glycoside from plants of Paeoniaceae family with diverse anticancer activities. J Pharm Pharmacol. 2020;72(4):483-495.
  • [1]. Xiang Y, et al. Paeoniflorin: a monoterpene glycoside from plants of Paeoniaceae family with diverse anticancer activities. J Pharm Pharmacol. 2020;72(4):483-495.
  • [2]. Cao BY, et al. Paeoniflorin, a potent natural compound, protects PC12 cells from MPP+ and acidic damage via autophagic pathway. J Ethnopharmacol. 2010;131(1):122-129.
  • [3]. Yan D, et al. Paeoniflorin, a novel heat shock protein-inducing compound. Cell Stress Chaperones. 2004;9(4):378-389.

安全信息

WGK Germany3
Signal word Warning
GHS Symbol
Safety Statements
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Precautionary statements
RTECSRT1200000
Storage condition 室温保存 0-10 0-10°C 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3530 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
REFERENCE :
   YKKZAJ Yakugaku Zasshi.  Journal of Pharmacy.  (Nippon Yakugakkai, 2-12-15
   Shibuya, Shibuya-ku, Tokyo 150, Japan)  No.1-    1881-
   Volume(issue)/page/year: 89,899,1969

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 9530 mg/kg
TOXIC EFFECTS :
   Behavioral - sleep
   Behavioral - somnolence (general depressed activity)
REFERENCE :
   YKKZAJ Yakugaku Zasshi.  Journal of Pharmacy.  (Nippon Yakugakkai, 2-12-15
   Shibuya, Shibuya-ku, Tokyo 150, Japan)  No.1-    1881-
   Volume(issue)/page/year: 89,899,1969

系列性分类

  1. Life Science 生命科学
  2. Nutrition Research 营养研究
  3. Phytochemicals by Chemical Classification - Nutrition Research
  4. Plant Extracts - Phytochemicals by Chemical Classification
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Carbohydrates - Biochemicals and Reagents
  4. Carbohydrates A to Z - Carbohydrates
  5. Carbohydrates P-Z - Carbohydrates A to Z
  1. Medical Research Areas
  2. Metabolism
  3. HSP  (热休克蛋白)

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