(12Z,6R,7R,8E,13E,15E,17S)-17-Hydroxy-6-Isopropyl-7,15-Dimethyl-32,33-Dihydro-31H-5-Oxa-11-Aza-1(4,2)-Oxazola-3(1,5)-Pyrrolacycloicosaphane-8,13,15-Triene-2,4,10,19-Tetraone (12Z,6R,7R,8E,13E,15E,17S)-17-羟基-6-异丙基-7,15-二甲基-32,33-二氢-31H-5-氧杂-11-氮杂-1(4,2)-噁唑-3(1,5)-吡咯环二十碳烷-8,13,15-三烯-2,4,10,19-四酮
CAS 21411-53-0 MFCD00869411
化学结构图
SMILES: CC1C=CCNC(=O)C=C[C@@H](C)[C@H](OC(=O)C2=CCCN2C(=O)C2=COC(CC(=O)C[C@H](O)C=1)=N2)C(C)C |c:34,t:2,8|
化学属性
| Mol. Formula | C28H35N3O7 |
|---|---|
| Mol. Weight | 526 |
| Melting Point | 165 - 170 |
别名和识别编码
| Chemical Name | (12Z,6R,7R,8E,13E,15E,17S)-17-Hydroxy-6-Isopropyl-7,15-Dimethyl-32,33-Dihydro-31H-5-Oxa-11-Aza-1(4,2)-Oxazola-3(1,5)-Pyrrolacycloicosaphane-8,13,15-Triene-2,4,10,19-Tetraone |
|---|---|
| CAS Number | 21411-53-0 |
| Synonym | ######## Mikamycin A Staphylomycin Mikamycin A Staphylomycin Virginiamycin M1 |
| MDL Number | MFCD00869411 |
| PubChem Substance ID | 24900736 |
| EC Number | 244-376-6 |
| Chemical Name Translation | (12Z,6R,7R,8E,13E,15E,17S)-17-羟基-6-异丙基-7,15-二甲基-32,33-二氢-31H-5-氧杂-11-氮杂-1(4,2)-噁唑-3(1,5)-吡咯环二十碳烷-8,13,15-三烯-2,4,10,19-四酮 |
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分类
- Chiral Reagents
- Heterocycles
- {SNA} Antibacterial, Antibiotics A to Z, Antibiotics T-Z, Chemical Structure Class, Interferes with Protein Synthesis, L - Z, Macrolides, Mechanism of Action, Spectrum of Activity, 抗生素, 生化试剂
- Pharmaceuticals
- {SNA} Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics T-Z, Chemical Structure Class, Interferes with Protein Synthesis, L - Z, Macrolides, Mechanism of Action, Spectrum of Activity
- Intermediates & Fine Chemicals
产品应用
- Macrolactone antibiotic. Antibacterial; growth promotant.
相关文献及参考
- Crooy, P., et al.: J. Antibiot., 25, 371 (1972),
- Allington, D., et al.: Clin. Therap., 23, 24 (2001),
- Eeman, M., et al.: Langmuir, 22, 11337 (2006),
安全信息
GHS Symbol
- S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
- P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛，皮肤或衣服。
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