Quinoline,2-((4-((2-(1H-tetrazol-5-ylmethyl)phenyl)methoxy)phenoxy)methyl)-

CAS 120128-20-3 MFCD00877828

化学结构图

120128-20-3
SMILES: C(C1NN=NN=1)C1C=CC=CC=1COC1C=CC(=CC=1)OCC1C=CC2C=CC=CC=2N=1

化学属性

Mol. FormulaC25H21N5O2
Mol. Weight423.51

别名和识别编码

Chemical NameQuinoline,2-((4-((2-(1H-tetrazol-5-ylmethyl)phenyl)methoxy)phenoxy)methyl)-
Synonym RG 12525 2-((4-((2-(1H-Tetrazol-5-ylmethyl)phenyl)methoxy)phenoxy)methyl)quinoline
Beilstein Registry Number3573814
CAS Number120128-20-3
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相关文献及参考

  • [2]. Fayer JL, et al. Lack of correlation between in vitro inhibition of CYP3A-mediated metabolism by a PPAR-gamma agonist and its effect on the clinical pharmacokinetics of midazolam, an in vivo probe of CYP3A activity. J Clin Pharmacol. 2001 Mar;41(3):305-16.
  • [3]. Carnathan GW, et al. The effect of RG 12525 on leukotriene D4-mediated pulmonary responses in guinea pigs. Agents Actions. 1989 Jun;27(3-4):316-8.
  • [1]. Van Inwegen RG, et al. Antagonism of peptidoleukotrienes and inhibition of systemic anaphylaxis by RG 12525 in guinea pigs. Life Sci. 1989;44(12):799-807.
  • [1]. Van Inwegen RG, et al. Antagonism of peptidoleukotrienes and inhibition of systemic anaphylaxis by RG 12525 in guinea pigs. Life Sci. 1989;44(12):799-807.
  • [2]. Fayer JL, et al. Lack of correlation between in vitro inhibition of CYP3A-mediated metabolism by a PPAR-gamma agonist and its effect on the clinical pharmacokinetics of midazolam, an in vivo probe of CYP3A activity. J

安全信息

RTECSVC3213500

系列性分类

  1. Medical Research Areas
  2. GPCR & G Protein
  3. Leukotriene Receptor  (白三烯受体)
  1. Medical Research Areas
  2. Metabolism
  3. Cytochrome P450  (细胞色素P450)

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