Salmeterol Xinafoate 昔美酸沙美特罗
CAS 94749-08-3 MFCD00897708
化学结构图
SMILES: OCC1=CC(=CC=C1O)C(O)CNCCCCCCOCCCCC1C=CC=CC=1.OC(=O)C1C=CC2C=CC=CC=2C=1O
化学属性
| Mol. Formula | C25H37NO4· C11H8O3 |
|---|---|
| Mol. Weight | 603.75 |
别名和识别编码
| Chemical Name | Salmeterol Xinafoate |
|---|---|
| CAS Number | 94749-08-3 |
| Synonym | ######## Salmeterol xinafoate |
| MDL Number | MFCD00897708 |
| PubChem Substance ID | 24278713 |
| Chemical Name Translation | 昔美酸沙美特罗 |
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分类
- Amines
- Aromatics
- Pharmaceuticals
- Intermediates & Fine Chemicals
- {SNA} Adrenergics, Adrenergics - Agonists, Agonists, Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, GlaxoSmithKline, Membrane Protein Biology Tools, Neuroscience, Neurotransmission, Neurotransmitters, Proteins and Derivatives, S
产品应用
- A ?2-Adrenergic agonist. Structural analog of Albuterol (A514500).
相关文献及参考
- [2]. Malcolm Johnson. Effects of beta2-agonists on resident and infiltrating inflammatory cells. J Allergy Clin Immunol. 2002 Dec;110(6 Suppl):S282-90.
- [3]. Zhiyuan Wang, et al. Efficacy of salmeterol and formoterol combination treatment in mice with chronic obstructive pulmonary disease. Exp Ther Med. 2018 Feb;15(2):1538-1545.
- Johnson, M.: Lung, 168, Suppl., 115 (1990),
- Ullman, A., et al.: Am. Rev. Resp. Dis., 142, 571 (1990),
- [1]. Panayiotis A Procopiou, et al. The discovery of long-acting saligenin β₂ adrenergic receptor agonists incorporating a urea group. Bioorg Med Chem. 2011 Oct 15;19(20):6026-32.
- [1]. Panayiotis A Procopiou, et al. The discovery of long-acting saligenin β₂ adrenergic receptor agonists incorporating a urea group. Bioorg Med Chem. 2011 Oct 15;19(20):6026-32.
- [2]. Malcolm Johnson. Effects of beta2-agonists on resident and infiltrating inflammatory cells. J Allergy Clin Immunol. 2002 Dec;110(6 Suppl):S282-90.
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