RO 46-2005 4-(叔丁基)-N-(6-(2-羟基乙氧基)-5-(3-甲氧基苯氧基)嘧啶-4-基)苯磺酰胺

CAS 150725-87-4 MFCD00918670

化学结构图

150725-87-4
SMILES: COC1C=C(C=CC=1)OC1C(=NC=NC=1NS(=O)(=O)C1=CC=C(C=C1)C(C)(C)C)OCCO

化学属性

Mol. FormulaC23H27N3O6S
Mol. Weight473.547

别名和识别编码

Chemical NameRO 46-2005
Chemical Name Translation4-(叔丁基)-N-(6-(2-羟基乙氧基)-5-(3-甲氧基苯氧基)嘧啶-4-基)苯磺酰胺
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相关文献及参考

  • [2]. Clozel M, et al. Pathophysiological role of endothelin revealed by the first orally active endothelin receptor antagonist. Nature. 1993 Oct 21;365(6448):759-761.
  • [3]. N.R. Sibson, et al. MRI Determination of the Mechanisms Underlying TNF-a-induced Changes in Cerebral Blood Volume, Tissue Water Diffusion and BBB Permeability. Proc. Intl. Soc. Mag. Reson. Med. 10 (2002)
  • [1]. Breu V, et al. In vitro characterization of Ro 46-2005, a novel synthetic non-peptide endothelin antagonist of ETA and ETBreceptors. FEBS Lett. 1993 Nov 15;334(2):210-214.
  • [1]. Breu V, et al. In vitro characterization of Ro 46-2005, a novel synthetic non-peptide endothelin antagonist of ETA and ETBreceptors. FEBS Lett. 1993 Nov 15;334(2):210-214.
  • [2]. Clozel M, et al. Pathophysiological role of endothelin revealed by the first orally active endothelin receptor antagonist. Nature. 1993 Oct 21;365(6448):759-761.
  • [3]. N.R. Sibson, et al. MRI Determination of the Me

系列性分类

  1. Medical Research Areas
  2. GPCR & G Protein
  3. Endothelin Receptor  (内皮素受体)

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