SR 59230A (S)-1-(2-乙基苯氧基)-3-(((S)-1,2,3,4-四氢萘-1-基)氨基)丙-2-醇草酸盐

CAS 174689-39-5 MFCD00940163

化学结构图

174689-39-5
SMILES: CCC1C=CC=CC=1OC[C@@H](O)CN[C@H]1CCCC2C=CC=CC=21.OC(=O)C(O)=O

化学属性

Mol. FormulaC21H27NO2· C2H2O4
Mol. Weight415.48

别名和识别编码

Chemical NameSR 59230A
Synonym 3-(2-Ethylphenoxy)-1-[[(1S)-1,2,3,4-tetrahydronaphth-1-yl]amino]-(2S)-2-propanol oxalate salt SR 59230A
MDL NumberMFCD00940163
PubChem Substance ID24278715
Chemical Name Translation(S)-1-(2-乙基苯氧基)-3-(((S)-1,2,3,4-四氢萘-1-基)氨基)丙-2-醇草酸盐
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分类

  • {SNA} Adrenergics, Adrenergics - Antagonists, Antagonists, Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Fluorination Ready Pharma-Developed Compounds, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, Membrane Protein Biology Tools, Neuroscience, Neurotransmission, Neurotransmission (Obesity), Neurotransmitters, S, Sanofi Aventis, 生化试剂, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学, 肥胖研究, 蛋白质及衍生物
  • {SNA} Adrenergics, Adrenergics - Antagonists, Antagonists, Approved Therapeutics/Drug Candidates,

相关文献及参考

  • [2]. Kanzler SA, et al. Involvement of β3-adrenergic receptors in the control of food intake in rats.Braz J Med Biol Res. 2011 Nov;44(11):1141-7.
  • [3]. Bruno G, et al. β3-adrenoreceptor blockade reduces tumor growth and increases neuronal differentiation in neuroblastoma via SK2/S1P2 modulation.Oncogene. 2020 Jan;39(2):368-384.
  • [4]. Bexis S, et al. Role of alpha 1- and beta 3-adrenoceptors in the modulation by SR59230A of the effects of MDMA on body temperature in the mouse. Br J Pharmacol. 2009 Sep;158(1):259-66.
  • [1]. Nisoli E, et al. Functional studies of the first selective beta 3-adrenergic receptor antagonist SR 59230A in rat brown adipocytes.Mol Pharmacol. 1996 Jan;49(1):7-14.
  • [1]. Nisoli E, et al. Functional studies of the first selective beta 3-adrenergic receptor antagonist SR 59230A in rat brown adipocytes.Mol Pharmacol. 1996 Jan;49(1):7-14.
  • [2]. Kanzler SA, et al. Involvement of β3-adrenergic receptors in the control of foo

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Bioactive Small Molecules - Cell Biology
  4. S - Bioactive Small Molecules
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Proteins and Derivatives - Biochemicals and Reagents
  4. Membrane Protein Biology Tools - Proteins and Derivatives
  5. GPCR Proteins, Modulators and Antibodies - Membrane Protein Biology Tools
  6. GPCR Modulators - GPCR Proteins, Modulators and Antibodies
  7. Adrenergics - Antagonists - GPCR Modulators
  1. Medical Research Areas
  2. GPCR & G Protein
  3. Adrenergic Receptor  (肾上腺素能受体)

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