4H-Imidazo(1,5-a)(1,4)benzodiazepine,8-chloro-6-(2-fluorophenyl)-1-methyl-,(Z)-2-butenedioate (1:1) 马来酸咪达唑仑

CAS 59467-94-6 MFCD00941440

化学结构图

59467-94-6
SMILES: CC1=NC=C2CN=C(C3=CC=CC=C3F)C3C=C(Cl)C=CC=3N21.OC(=O)/C=C\C(O)=O

化学属性

Mol. FormulaC18H13ClFN3.C4H4O4
Mol. Weight441.87

别名和识别编码

Chemical Name4H-Imidazo(1,5-a)(1,4)benzodiazepine,8-chloro-6-(2-fluorophenyl)-1-methyl-,(Z)-2-butenedioate (1:1)
Synonym Midazolam maleate salt 8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo(1,5-a)(1,4)benzodiazepine
MDL NumberMFCD00941440
PubChem Substance ID24896731
EC Number261-775-0
Wiswesser Line NotationT B576 BN DN HN GHJ C1 IR BF& LG &QV1U1VQ
CAS Number59467-94-6
Chemical Name Translation马来酸咪达唑仑
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分类

  • {SNA} Approved Therapeutics/Drug Candidates, Benzodiazepines and Anxiolytics, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, M, Neurobiology, Neuroscience, Pharmacologicals, Roche

安全信息

RTECSNI2922200
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
GHS Symbol
Hazard statements
  • H302 Harmful if swallowed 吞食有害
WGK Germany3
Signal word Warning
Safety Statements
  • S36 Wear suitable protective clothing 穿戴适当的防护服;
Hazard Codes Xn
Risk Statements
  • R22 Harmful if swallowed 吞咽有害
Restrict {} 精神药品 精麻类化学品
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 86 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 31,2180,1981

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 760 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 31,2180,1981

系列性分类


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