YIC-C8-434

CAS 214265-97-1 MFCD00954689

化学结构图

214265-97-1
SMILES: CCCCCCCCOC1C(=CC(=CC=1OC)/C=C/C(=O)N1CCN(CC1)C1=CC(C)=C(C)C=C1)OC

化学属性

Mol. FormulaC31H44N2O4
Mol. Weight508.69
Melting Point103.6-105.2 °C

别名和识别编码

Chemical NameYIC-C8-434
Synonym N-(3,5-Dimethoxy-4-n-octyloxycinnamoyl)-N′-(3,4-dimethylphenyl)piperazine N-(3,5-Dimethoxy-4-n-octyloxycinnamoyl)-N'-(3,4-dimethylphenyl)piperazine
MDL NumberMFCD00954689
PubChem Substance ID24724670
CAS Number214265-97-1
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分类

  • {SA} A to C, Acyl-CoA Cholesterol O-Acyltransferase, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, Y
  • {SNA} A to C, Acyl-CoA Cholesterol O-Acyltransferase, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, 生化试剂, 酶、抑制剂和底物

相关文献及参考

  • Ohishi, K., et al., Inhibitory effects of N-(3,5-dimethoxy-4-n-octyloxycinnamoyl)-N'-(3,4-dimethylphenyl)piperazine (YIC-C8-434), an acyl-CoA:cholesterol O-acyltransferase inhibitor, on cholesterol esterification in the intestine and liver. Biol. Pharm. Bull. 26 , 1125-1128, (2003)
  • Kaneko, K., et al., Sex-dependent toxicity of a novel acyl-CoA:cholesterol acyltransferase inhibitor, YIC-C8-434, in relation to sex-specific forms of cytochrome P450 in rats. Toxicol. Sci. 64 , 259-268, (2001)

安全信息

Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
WGK Germany3

系列性分类

  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Enzyme Inhibitors - Enzymes, Inhibitors, and Substrates
  5. Enzyme Inhibitors by Enzyme - Enzyme Inhibitors
  6. A to C - Enzyme Inhibitors by Enzyme
  7. Acyl-CoA Cholesterol O-Acyltransferase - A to C

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