Oncrasin 1 昂克立新 1

CAS 75629-57-1 MFCD01051808

化学结构图

75629-57-1
SMILES: O=CC1=CN(CC2C=CC(Cl)=CC=2)C2C=CC=CC=21

化学属性

Mol. FormulaC16H12ClNO
Mol. Weight270
TSCANo
Melting Point115.0 to 119.0 deg-C

别名和识别编码

Chemical NameOncrasin 1
CAS Number75629-57-1
Alfabeta NameCHLOROBENZYLINDOLECARBALDEHYDE H1413()------
MDL NumberMFCD01051808
Synonym 1-[(4-Chlorophenyl)methyl]-1H-indole-3-carboxaldehyde Oncrasin-1
PubChem Substance ID253660594
Chemical Name Translation昂克立新 1
Reaxys-RN5549127
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分类

  • {SNA} Aldehydes, Bioactive Small Molecule Alphabetical Index, Building Blocks, C13-C60, Carbonyl Compounds, Chemical Synthesis, Gene Regulation, Gene Regulation and Expression, O, Organic Building Blocks, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
  • {SNA} Aldehydes, Bioactive Small Molecules, Building Blocks, C13-C60, Carbonyl Compounds, Cell Biology, Cell Signaling and Neuroscience, Chemical Synthesis, Gene Regulation, Gene Regulation and Expression, O, Organic Building Blocks

相关文献及参考

  • [2]. Guo W, et al. Interruption of RNA processing machinery by a small compound, 1-[(4-chlorophenyl)methyl]-1H-indole-3-carboxaldehyde (oncrasin-1). Mol Cancer Ther. 2009 Feb;8(2):441-8.
  • [1]. Guo W, et al. Identification of a small molecule with synthetic lethality for K-ras and protein kinase C iota. Cancer Res. 2008 Sep 15;68(18):7403-8.
  • [1]. Guo W, et al. Identification of a small molecule with synthetic lethality for K-ras and protein kinase C iota. Cancer Res. 2008 Sep 15;68(18):7403-8.
  • [2]. Guo W, et al. Interruption of RNA processing machinery by a small compound, 1-[(4-chlorophenyl)methyl]-1H-indole-3-carboxaldehyde (oncrasin-1). Mol Cancer Ther. 2009 Feb;8(2):441-8.

安全信息

Warnings IRRITANT
WGK Germany3
Storage condition 0-10°C Light Sensitive
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
GHS Symbol
Signal word
Precautionary statements
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P352+P332+P313+P362+P364
  • P305+P351+P338+P337+P313

系列性分类


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