3-(3-((Benzo[d]thiazol-2-ylthio)methyl)-4-hydroxy-5-methoxyphenyl)-2-cyanoacrylamide 3-(3-((苯并[d]噻唑-2-基硫代)甲基)-4-羟基-5-甲氧基苯基)-2-氰基丙烯酰胺

CAS 149092-50-2 MFCD01074971

化学结构图

149092-50-2
SMILES: COC1C=C(C=C(CSC2=NC3=CC=CC=C3S2)C=1O)/C=C(\C#N)/C(N)=O

化学属性

Mol. FormulaC19H15N3O3S2
Mol. Weight397.47
TSCANo

别名和识别编码

Chemical Name3-(3-((Benzo[d]thiazol-2-ylthio)methyl)-4-hydroxy-5-methoxyphenyl)-2-cyanoacrylamide
Synonym 5-[(Benzothiazol-2-yl)thiomethyl]-4-hydroxy-3-methoxybenzylidenecyanoacetamide 5-[(Benzothiazol-2-yl)thiomethyl]-4-hydroxy-3-methoxybenzylidenecyanoacetamide Tyrphostin C15 AG 825 Tyrphostin AG 825 Tyrphostin C15
MDL NumberMFCD01074971
CAS Number149092-50-2
PubChem Substance ID329826823
Chemical Name Translation3-(3-((苯并[d]噻唑-2-基硫代)甲基)-4-羟基-5-甲氧基苯基)-2-氰基丙烯酰胺
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分类

  • {SNA} Bioactive Small Molecule Alphabetical Index, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Epidermal Growth Factor Receptor (EGFR), Kinase/Phosphatase Biology, P to Q, Protein Kinase Inhibitors, Protein kinase, tyrosine, EGF receptor, Protein kinase, tyrosine, HER-1, Receptor Tyrosine Kinase Biology, Receptor Tyrosine Kinase Inhibitors, T, 生化试剂, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学, 酶、抑制剂和底物
  • {SNA} Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme,

相关文献及参考

  • Parrrizas, M., Specific inhibition of Insulin-like growth factor-1 and insulin receptor tyrosine kinase activity and biological function by tyrphostins. Endocrinology 138 , 1427, (1997) 摘要
  • Osherov, N., et al., Selective inhibition of the epidermal growth factor and HER2/neu receptors by tyrphostins. J. Biol. Chem. 268 , 11134, (1993) 摘要

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Storage condition Light Sensitive

系列性分类


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