Bisindolylmaleimide XI hydrochloride
CAS 151342-35-7 MFCD01319127
化学结构图
SMILES: Cl.CN(C)CC1CC2=CC3C=CC(=CC=3N2CC1)C1=C(C2=CN(C)C3C=CC=CC=32)C(=O)NC1=O
化学属性
| Mol. Formula | C28H28N4O2· HCl |
|---|---|
| Mol. Weight | 489.01 |
别名和识别编码
| Chemical Name | Bisindolylmaleimide XI hydrochloride |
|---|---|
| Synonym | Bisindolylmaleimide XI hydrochloride Bisindoylmaleimide XI; 2-(8-[(Dimethylamino)methyl]-6,7,8,9-tetrahydropyrido[1,2-a]indol-3-yl)-3-(1-methylindol-3-yl)maleimide Ro 32-0432 |
| MDL Number | MFCD01319127 |
| PubChem Substance ID | 329773227 |
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分类
- {SNA} Cell Biology, Cell Signaling and Neuroscience, Kinase/Phosphatase Biology, Peptides and Proteins, Peptides for Cell Biology, Protein Kinase C (PKC), Protein Kinase Inhibitors, Protein Kinase Related Peptides,
- {SNA} B, Bioactive Small Molecule Alphabetical Index, Kinase/Phosphatase Biology, Peptides and Proteins, Peptides for Cell Biology, Protein Kinase C (PKC), Protein Kinase Inhibitors, Protein Kinase Related Peptides, Serine/Threonine Kinase Biology, Serine/Threonine Kinase Inhibitors, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
- Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology,
相关文献及参考
- Moore, J.B., et al., Inhibition of PTH desensitization by inhibition of the G protein-coupled receptor kinase-5 enzyme with Ro 32-0432. FASEB J. 12 , A741, (1998)
- Wilkinson, S.E., et al., Isoenzyme specificity of bisindolylmaleimides, selective inhibitors of protein kinase C. Biochem. J. 294 , 335-337, (1993) 摘要
- Gozal, D., et al., Cardiorespiratory responses to systemic administration of a protein kinase C inhibitor in conscious rats. J. Appl. Physiol. 84 , 641-648, (1998) 摘要
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