3-Phenyl-1H-Benzofuro[3,2-c]Pyrazole 3-苯基-1H-苯并呋喃并[3,2-c]吡唑

CAS 34823-86-4 MFCD01416326

化学结构图

34823-86-4
SMILES: c1ccc(-c2n[nH]c3c2oc2ccccc23)cc1

化学属性

Mol. FormulaC15H10N2O
Mol. Weight234.25
Appearance Solid powder
SolubilitySoluble in DMSO, not in water

别名和识别编码

Chemical Name3-Phenyl-1H-Benzofuro[3,2-c]Pyrazole
FormulaC15H10N2O
Synonym GTP14564; GTP 14564; GTP-14564
IUPAC Name3-phenyl-1H-benzofuro[3,2-c]pyrazole
InChIKeyDZQLVVLATXPWBK-UHFFFAOYSA-N
InChIInChI=1S/C15H10N2O/c1-2-6-10(7-3-1)13-15-14(17-16-13)11-8-4-5-9-12(11)18-15/h1-9H,(H,16,17)
Canonical SMILESC12=C(OC3=CC=CC=C32)C(C4=CC=CC=C4)=NN1
Chemical Name Translation3-苯基-1H-苯并呋喃并[3,2-c]吡唑
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产品应用

  • GTP-14564 is a specific kinase inhibitor for ITD-FLT3. GTP-14564 inhibited the growth of interleukin-3-independent Ba/F3 expressing ITD-FLT3 at 1 microM, whereas a 30-fold higher concentration of GTP-14564 was required to inhibit FLT3 ligand-dependent growth of Ba/F3 expressing wild type FLT3 (wt-FLT3).

安全信息

Storage condition Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

系列性分类

  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Pyrazoles 吡唑
  1. Medical Research Areas
  2. Angiogenesis
  3. FLT3

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