5-(2,3-Dimethylbenzyl)-1H-Imidazole Hydrochloride 5-(2,3-二甲基苄基)-1H咪唑盐酸盐
CAS 90038-01-0 MFCD01721520
化学结构图
SMILES: Cl.CC1=C(CC2=CNC=N2)C=CC=C1C
化学属性
| Mol. Formula | C12H15ClN2 |
|---|---|
| Mol. Weight | 223 |
别名和识别编码
| Chemical Name | 5-(2,3-Dimethylbenzyl)-1H-Imidazole Hydrochloride |
|---|---|
| CAS Number | 90038-01-0 |
| Synonym | Detomidina 5-[(2,3-Dimethylphenyl)methyl]-1H-imidazole Hydrochloride 4-((2,3-Dimethylphenyl)methyl)-1H-imidazole hydrochloride Domosedan Detomidine hydrochloride MPV 253AII 4-(2',3'-Dimethylbenzyl)imidazole hydrochloride Dormosedan 4-[(2,3-Dimethylphenyl)methyl]-1H-imidazole Monohydrochloride |
| Chemical Name Translation | 5-(2,3-二甲基苄基)-1H咪唑盐酸盐 |
| MDL Number |
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资金保障
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分类
- Aromatics
- Heterocycles
- Pharmaceuticals
- Intermediates & Fine Chemicals
产品应用
- ?-Adrenoceptor agonist with sedative and analgesic activity. Sedative.
相关文献及参考
- [2]. J Still, et al. Cardiovascular and respiratory effects of detomidine in isoflurane-anaesthetised horses. J S Afr Vet Assoc. 1996 Dec;67(4):199-203.
- Laine, E., Acta Pharm. Suec., 20, 451 (1983),
- Virtanen, R., et al.: Eur. J. Pharmacol., 108, 163 (1985),
- [1]. Virtanen R, et al. Pharmacological evidence for the involvement of alpha-2 adrenoceptors in the sedative effect of detomidine, a novel sedative-analgesic. J Vet Pharmacol Ther. 1985 Mar;8(1):30-7.
- [1]. Virtanen R, et al. Pharmacological evidence for the involvement of alpha-2 adrenoceptors in the sedative effect of detomidine, a novel sedative-analgesic. J Vet Pharmacol Ther. 1985 Mar;8(1):30-7.
- [2]. J Still, et al. Cardiovascular and respiratory effects of detomidine in isoflurane-anaesthetised horses. J S Afr Vet Assoc. 1996 Dec;67(4):199-203.
安全信息
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 35 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4443466
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