CRM-STX-E

CAS 35554-08-6 MFCD01749871

化学结构图

35554-08-6
SMILES: Cl.Cl.NC1N[C@@]23[C@@H](N=1)[C@H](COC(N)=O)N=C(N)N2CCC3(O)O

化学属性

Mol. FormulaC10H17N7O4.2ClH
Mol. Weight372.26

别名和识别编码

Chemical Name1H,10H-Pyrrolo(1,2-C)purine-10,10-diol,3a,4,8,9-tetrahydro-2,6-diamino-4-(((aminocarbonyl)oxy)methyl)-, dihydrochloride,(3aS-(3a-alpha,4-alpha,10aR*))-
Wiswesser Line NotationT565 1A L AXMYM GMYN EH&TTJ CUM F1OVZ HUM LQ LQ &GH 2
Synonym Saxitoxin hydrochloride Saxitoxin dihydrochloride Mussel poison dihydrochloride Paralytic shellfish poison dihydrochloride Clam poison dihydrochloride Biclorhidrato de saxotoxina Gonyaulax catenella poison dihydrochloride Gonyaulax toxic dihydrochloride STX dihydrochloride
CAS Number35554-08-6
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安全信息

RTECSUY8708600
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Parenteral
SPECIES OBSERVED        : Mammal - domestic
DOSE/DURATION           : >126 ng/kg
TOXIC EFFECTS :
   Behavioral - general anesthetic
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #3892847

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 3 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   14FHAR "Venomous and Poisonous Animals and Noxious Plants of the Pacific
   Region," Keegan, H.L., and W.V. Macfarlane, eds., New York, Pergamon Press
   Inc., 1963  Volume(issue)/page/year: -,75,1963

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 263 ug/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   2,607,1960

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 8 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   2,607,1960

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 85 ug/kg
TOXIC EFFECTS :
   Details of toxic effects

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