(E)-6-(3,4-DiHydroxystyryl)-4-Hydroxy-2H-Pyran-2-One (E)-6-(3,4-二羟基苯乙烯基)-4-羟基-2H-吡喃-2-酮
CAS 555-55-5 MFCD01866972
化学结构图
SMILES: O=c1cc(O)cc(C=Cc2ccc(O)c(O)c2)o1
化学属性
| Mol. Weight | 246.215 |
|---|---|
| Mol. Formula | C13 H10 O5 |
| Melting Point | 312-315 ºC |
| Density | 1.657 |
别名和识别编码
| Synonym | 6-(3,4-dihydroxystyrl)-4-hydroxy-2-pyrone 6-[(1E)-2-(3,4-Dihydroxyphenyl)ethenyl]-4-hydroxy-2H-pyran-2-one; 6-(3,4-Dihydroxystyryl)-4-hydroxy-2H-pyran-2-one; (E)-6-[2-(3,4-Dihydroxyphenyl)ethenyl]-4-hydroxy-2H-pyran-2-one; 6-(3,4-Dihydroxystyryl)-4-hydroxy-2-pyrone Hispidin |
|---|---|
| MDL Number | MFCD01866972 |
| PubChem Substance ID | 54685921 |
| CAS Number | 555-55-5 |
| Chemical Name | (E)-6-(3,4-DiHydroxystyryl)-4-Hydroxy-2H-Pyran-2-One |
| Chemical Name Translation | (E)-6-(3,4-二羟基苯乙烯基)-4-羟基-2H-吡喃-2-酮 |
| InChIKey | SGJNQVTUYXCBKH-HNQUOIGGSA-N |
| InChI | InChI=1S/C13H10O5/c14-9-6-10(18-13(17)7-9)3-1-8-2-4-11(15)12(16)5-8/h1-7,14-16H/b3-1+ |
| LabNetwork Molecule ID | LN04681775 |
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分类
- {SNA} Antitumor Agents,
- {SNA} Antitumor Agents, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, H, Kinase/Phosphatase Biology, P to Q, Protein Kinase C (PKC), Protein Kinase C beta, Protein Kinase Inhibitors, Protein kinase C, Serine/Threonine Kinase Biology, Serine/Threonine Kinase Inhibitors, 癌症研究
- {SNA} Bioactive Small Molecule Alphabetical Index, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, H, Kinase/Phosphatase Biology, P to Q,
相关文献及参考
- Gonindard, C., et al., Synthetic hispidin, a PKC inhibitor, is more cytotoxic toward cancer cells than normal cells in vitro. Cell Biol. Toxicol. 13 , 141-153, (1997) 摘要
- [1]. Kim DE, et al. The protective effect of hispidin against hydrogen peroxide-induced apoptosis in H9c2 cardiomyoblast cells through Akt/GSK-3β and ERK1/2 signaling pathway. Exp Cell Res. 2014 Oct 1;327(2):264-75.
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