CAS 41468-25-1 MFCD00006333-(4-Formyl-5-hydroxy-6-methylpyridin-3-yl)methyl dihydrogen phosphate hydrate 磷酸-5-吡哆醛一水合物 -LabNovo

(4-Formyl-5-hydroxy-6-methylpyridin-3-yl)methyl dihydrogen phosphate hydrate 磷酸-5-吡哆醛一水合物

CAS 41468-25-1 MFCD00006333

化学结构图

SMILES: Cc1ncc(COP(=O)(O)O)c(C=O)c1O.O

化学属性

Mol. Formula	C8H10NO6P·H2O
Mol. Weight	247.14(as Anhydrous)
Melting Point	140-143 °C
Appearance	powder 50 (大鼠，经口)5900 mg/kg。白色结晶性粉末，无气味，在碱性溶液中呈亮黄色。水溶液避光低温稳定，见光渐分解。易溶于甲酸、含水吡啶和稀碱液，微溶于水、乙醇、丙酮、氯仿和乙醚等有机溶剂。LD
Density	1.638

别名和识别编码

Chemical Name	(4-Formyl-5-hydroxy-6-methylpyridin-3-yl)methyl dihydrogen phosphate hydrate
Synonym	CODECARBOXYLASE hairoxal Pyridoxal 5'-phosphate hydrate 吡多醛磷酸酯磷酸吡哆醛 3-hydroxy-2-methyl-5-((phosphonooxy)methyl)-4-pyridinecarboxaldehyd PYRIDOXAL 5'-MONOPHOSPHATE PYRIDOXAL-5-PHOSPHORIC ACID pal-p hexerminp phosphoridoxalcoenzyme biosechs PYRIDOXAL 5'-PHOSPHATE 3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]-4-PYRIDINECARBOXALDEHYDE Codecarboxylase 3-羟基-2-甲基-5-[(磷酰氧基)甲基]-4-吡啶甲醛吡哆醛 5-磷酸酯 hi-pyridoxin 3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]-4-pyridinecarboxaldehyd 3-羟基-2-甲基-5-[(膦羧基)甲基]-4-吡啶醛,3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]4-PYRINECAR-BOXALDEHYDE 吡多醛-5-磷酸酯 piodel PYRIDOXAL 5-PHOSPHATE phosphopyridoxal VITAMIN B6 3-Hydroxy-2-methyl-5-([phosphonooxy]methyl)-4-pyridinecarboxaldehyde Codecarboxylase PLP Pyridoxal 5-phosphate Pyridoxal phosphate 3-Hydroxy-2-methyl-5-([phosphonooxy]methyl)-4-pyridinecarboxaldehyde Codecarboxylase PLP Pyridoxal 5-phosphate 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde 5-phosphate
MDL Number	MFCD00006333
Beilstein Registry Number	234749
EC Number	200-208-3
PubChem Substance ID	87565509
Reaxys-RN	234749
CAS Number	41468-25-1
Merck Number	7979
Chemical Name Translation	磷酸-5-吡哆醛一水合物
Wiswesser Line Notation	T6NJ B1 CQ DVH E1OPQQO &QH

信息真实价格透明资金保障专业采购外包团队在线服务

品牌质保精细包装现货库存一流品牌服务

产品应用

酶辅助因子， Vitamin B6的正常辅酶形式。

安全信息

WGK Germany3

Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

RTECSUV1208000

Storage condition -20°C 储存温度 -20°C

Safety Statements

GHS Symbol

Precautionary statements

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 870 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 11,922,1961

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 5900 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - excitement
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 11,922,1961

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 4640 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 11,922,1961

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 850 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - excitement
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 11,922,1961

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其他信息

磷酸吡哆醛价格(试剂级):更新日期产品编号产品名称包装价格 2011/08/23 67001332 磷酸-5’-吡哆醛(+4℃) 5g 50元
图谱信息:磷酸吡哆醛(54-47-7)红外图谱(IR2) 磷酸吡哆醛(54-47-7)红外图谱(IR1)
用途一:生化研究，孕甾酮特性的结构修饰，酶抑制剂。
用途二:维生素B6的主体药物，适用于治疗急慢性湿疹、皮肤炎、荨麻诊、脓疱疹、搔痒症、脂溢性湿疹、鳞屑疹、药疹、口角炎、口唇炎、舌炎、妊娠反应、哮喘等。该品实际上无毒，大鼠口服LD50为6g/kg。
上游原料:二氧化锰 --> 五氧化二磷 --> 磷酸酯 --> 吡多素 --> 盐酸吡多胺
方法一:吡哆胺二盐酸盐与无水磷酸反应成吡哆胺磷酸酯，后者再经二氧化锰氧化制得。
MSDS 信息:3-Hydroxy-2-methyl-5-[(phosphonooxy)methyl]-4-pyridinecarboxaldehyde(54-47-7).msds
Sigma Aldrich:54-47-7(sigmaaldrich)
下游产品:4-脱氧吡哆醇盐酸盐
F:8-10-23
参考质量标准:紫外光谱检测合格。
方法二:以吡哆醇为原料。
MOL 文件:54-47-7.mol