2-AMINO-N'-(4-HYDROXY-3-METHOXYBENZYLIDENE)-4-METHYL-1,3-THIAZOLE-5-CARBOHYDRAZIDE

CAS 292170-13-9 MFCD02086738

化学结构图

292170-13-9
SMILES: CC1N=C(N)SC=1C(=O)N/N=C/C1=CC(OC)=C(O)C=C1

化学属性

Mol. FormulaC13H14N4O3S
Mol. Weight306.34

别名和识别编码

Chemical NameOM137
Synonym 2-Amino-N′-(4-hydroxy-3-methoxybenzylidene)-4-methyl-1,3-thiazole-5-carbohydrazide 2-Amino-N'-(4-hydroxy-3-methoxybenzylidene)-4-methyl-1,3-thiazole-5-carbohydrazide 5-Thiazolecarboxylic acid, 2-amino-4-methyl-, 2-[(4-hydroxy-3-methoxyphenyl)methylene]hydrazide 5-Thiazolecarboxylic acid, 2-amino-4-methyl-, 2-[(4-hydroxy-3-methoxyphenyl)methylene]hydrazide
MDL NumberMFCD02086738
CAS Number292170-13-9
PubChem Substance ID329818924
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分类

  • Cell Biology, Cell Signaling and Neuroscience, Kinase/Phosphatase Biology, Protein Kinases (PK), Serine/Threonine Kinase Biology, Serine/Threonine Kinase Inhibitors
  • {SNA} Bioactive Small Molecule Alphabetical Index, Kinase/Phosphatase Biology, O, Protein Kinases (PK), Serine/Threonine Kinase Biology, Serine/Threonine Kinase Inhibitors, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学

相关文献及参考

  • DeMoe, J.H., et al., A high throughput, whole cell screen for small molecule inhibitors of the mitotic spindle checkpoint identifies OM137, a novel Aurora kinase inhibitor. Cancer Res. 69 , 1509-1516, (2009) 摘要

安全信息

GHS Symbol
WGK Germany3
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
Signal word Warning
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H302 Harmful if swallowed 吞食有害
  • H319 Causes serious eye irritation 严重刺激眼睛
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
Hazard Codes Xn
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R22 Harmful if swallowed 吞咽有害

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Kinase/Phosphatase Biology - Cell Signaling and Neuroscience
  5. Serine/Threonine Kinase Biology - Kinase/Phosphatase Biology
  6. Serine/Threonine Kinase Inhibitors - Serine/Threonine Kinase Biology
  7. Protein Kinases (PK) - Serine/Threonine Kinase Inhibitors

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