3,4,5-Trifluorobenzeneboronic Acid 3,4,5-三氟苯硼酸

CAS 143418-49-9 MFCD02093069

化学结构图

143418-49-9
SMILES: OB(O)C1=CC(F)=C(F)C(F)=C1

化学属性

Mol. FormulaC6H4BF3O2
Mol. Weight176
Melting Point290-295
TSCANo
Density1.44

别名和识别编码

Chemical Name3,4,5-Trifluorobenzeneboronic Acid
CAS Number143418-49-9
Alfabeta NameTRIFLUOROPHENYLBORONICACID 345-,,
MDL NumberMFCD02093069
Synonym 3,4,5-三氟苯硼酸 3,4,5-Trifluorophenylboronic acid 3,4,5-Trifluorobenzeneboronic acid
PubChem Substance ID24874437
EC Number250-023-7
Beilstein Registry Number7371914
Chemical Name Translation3,4,5-三氟苯硼酸
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分类

  • Aryl Boronic Acids, Boronic Acids, Boronic Acids and Derivatives, Chemical Synthesis, Organometallic Reagents, Trisubstituted Aryl Boronic Acids
  • {SNA} Aryl Boronic Acids, Boronic Acids, Boronic Acids and Derivatives, Chemical Synthesis, Organometallic Reagents, Trisubstituted Aryl Boronic Acids

相关文献及参考

  • 1. A. Adamczyk-Wozniak, et al., , Quantitative determination of the Lewis acidity of phenylboronic catechol esters - Promising anion receptors for polymer electrolytes Inorg. Chem. Commun. 14 , 1753-1755, (2011)
  • 2. N. Gavande, et al., , Identification of Benzopyran-4-one Derivatives (Isoflavones) as Positive Modulators of GABAA Receptors ChemMedChem 6 , 1340-1346, (2011)
  • 3. W. Jin, et al., , Regio- and Stereoselective Synthesis of Multisubstituted Olefins and Conjugate Dienes by Using a-Oxo Ketene Dithioacetals as the Building Blocks Org. Lett. 13 , 4272-4275, (2011)
  • 4. Z. Zhou, et al., , Suzuki cross-coupling reactions of aryl chlorides using [Cl2Pd(COD)]/piperazine derivative under microwave conditions Appl. Organomet. Chem. 25 , 616-619, (2011)
  • 5. N. Liu, et al., , Green synthesis of fluorinated biaryl derivatives via thermoregulated ligand/palladium-catalyzed Suzuki reaction J. Organomet. Chem. 696 , 2641-2647, (2011)
  • 6. H. Behniafar and M. Sedaghatdoost, , New fluorinated aromatic poly(ether-amide)s derived from 2,2'-bis(3,4,5-trifluorophenyl)-4,4'-diaminodiphenyl ether and various dicarboxylic acids J. Fluor. Chem. 132 , 276-284, (2011)
  • Extremely active catalyst for the reaction of carboxylic acids with primary and secondary amines to give the corresponding amides in very high yields: J. Org. Chem., 61, 4196 (1996).
  • Extremely active catalyst for the reaction of carboxylic acids with primary and secondary amines to give the corresponding amides in very high yields: J. Org. Chem., 61, 4196 (1996). Also useful in the one-pot synthesis of acyl azides from carboxylic acids and NaN3: Tetrahedron Lett., 43, 9715 (2002). Mediates the mild, one-pot reduction of carboxylic acids to alcohols with NaBH4: Tetrahedron Lett., 44, 3427 (2003).
  • For other boronic acid chemistry, see Appendix 5.

安全信息

Warnings IRRITANT
WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S37 Wear suitable gloves 戴适当手套;
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
Risk Statements
  • R22 Harmful if swallowed 吞咽有害
  • R36 Irritating to eyes 刺激眼睛
  • R51/53
Signal word Warning
GHS Symbol
Precautionary statements
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P305+P351+P338
UN Number 3077
Hazard Codes 9
Packing GroupIII

系列性分类


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