4-Fluoro-3-Formylphenylboronic Acid 4-氟-3-醛基苯硼酸

CAS 374538-01-9 MFCD02093074

化学结构图

374538-01-9
SMILES: OB(O)C1C=CC(F)=C(C=O)C=1

化学属性

Mol. FormulaC7H6BFO3
Mol. Weight168
Melting Point215-220 °C
TSCANo

别名和识别编码

Chemical Name4-Fluoro-3-Formylphenylboronic Acid
CAS Number374538-01-9
Alfabeta NameFLUOROFORMYLBENZENEBORONICACID 43---
MDL NumberMFCD02093074
Synonym 4-氟-3-醛基苯硼酸 5-Borono-2-fluorobenzaldehyde
EC Number000-000-0
Beilstein Registry Number9046762
Chemical Name Translation4-氟-3-醛基苯硼酸
PubChem Substance ID354333294
Reaxys-RN9046762
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分类

  • {SNA} Aldehydes, Aryl Boronic Acids, Boronic Acids, Boronic Acids and Derivatives, Building Blocks, C7, Carbonyl Compounds, Chemical Synthesis, Disubstituted Aryl Boronic Acids, Organic Building Blocks, Organometallic Reagents
  • Aldehydes, Aryl Boronic Acids,

相关文献及参考

  • 1. Grob, J. E.; et al., One-pot reductive amination and Suzuki-Miyaura cross-coupling of formyl aryl and heteroaryl MIDA boronates in array format J. Org. Chem. 76 , 4930-4940, (2011)
  • 2. Pickett, S. D.; et al., Automated Lead Optimization of MMP-12 Inhibitors Using a Genetic Algorithm ACS Med. Chem. Lett. 2 , 28-33, (2011)
  • 3. Holland, R.; et al., Synthesis of para-substituted 3-formyl arylboronic esters Synthesis , 2379-2382, (2002)

安全信息

Warnings IRRITANT, AIR SENSITIVE
WGK Germany3
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S37 Wear suitable gloves 戴适当手套;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Storage condition Air Sensitive
Signal word
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
GHS Symbol
Precautionary statements
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P352+P332+P313+P362+P364
  • P305+P351+P338+P337+P313

系列性分类


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