N6-(4-AMINOBENZYL)-N-METHYLCARBOXAMIDOADENOSINE
CAS 152918-26-8 MFCD02094625
化学结构图
SMILES: CNC(=O)N(CC1C=CC(N)=CC=1)C1=NC=NC2=C1N=CN2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
化学属性
| Mol. Formula | C18H21N7O4 |
|---|---|
| Mol. Weight | 399.40 |
别名和识别编码
| Chemical Name | AB-MECA |
|---|---|
| Synonym | N6-(4-Aminobenzyl)-9-[5-(methylcarbonyl)-β-D-ribofuranosyl]adenine N6-(4-Aminobenzyl)-9-[5-(methylcarbonyl)-β-D-ribofuranosyl]adenine N6-(4-Aminobenzyl)-N-methylcarboxamidoadenosine N6-(4-Aminobenzyl)-N-methylcarboxamidoadenosine |
| PubChem Substance ID | 24277694 |
| CAS Number | 152918-26-8 |
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分类
- A-AM, Adenosines/P2 Nucleotide Receptor - Agonists, Adenosines/P2 Nucleotide Receptors (Purinergics), Agonists, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience,
- {SNA} A-AM, Adenosines/P2 Nucleotide Receptor - Agonists, Adenosines/P2 Nucleotide Receptors (Purinergics), Agonists, Bioactive Small Molecule Alphabetical Index, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, Membrane Protein Biology Tools, Neuroscience, Neurotransmission, Neurotransmitters, 生化试剂, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学, 蛋白质及衍生物
相关文献及参考
- Gallo-Rodriguez, et al., Structure-activity relationships of N 6 -benzyladenosine-5′-uronamides as A 3 selective adenosine agonists. J. Med. Chem. 37 , 636-646, (1994) 摘要
- Jacobson, et al., A role for central A 3 -adenosine receptors. Mediation of behavioral depressant effects. FEBS Lett. 336 , 57-60, (1993) 摘要
- Olah, et al., 125 I-4-Aminobenzyl-5′-N-methylcarboxamidoadenosine, a high affinity radioligand for the rat A 3 adenosine receptor. Mol. Pharmacol. 45 , 978-982, (1994) 摘要
- [1]. Shearman LP, et al. [125I]4-aminobenzyl-5'-N-methylcarboxamidoadenosine (125I)AB-MECA) labels multiple adenosine receptorsubtypes in rat brain. Brain Res. 1997 Jan 16;745(1-2):10-20.
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