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BRL 44408
CAS 118343-19-4 MFCD02262218
化学结构图
SMILES: CC1C2=CC=CC=C2CN1CC1NCCN=1.OC(=O)/C=C\C(O)=O
化学属性
Mol. Formula
C17H21N3O4
Mol. Weight
331.37
别名和识别编码
Chemical Name
BRL 44408 maleate salt
CAS Number
118343-19-4 (free base)
Synonym
2-[(4,5-Dihydro-1H-imidazol-2-yl)methyl]-2,3-dihydro-1-methyl-1H-isoindole 2-[2H-(1-Methyl-1,3-dihydroisoindole)methyl]-4,5-dihydroimidazole maleate salt
MDL Number
MFCD02262218
PubChem Substance ID
329773239
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分类
Adrenergics, Adrenergics - Antagonists, Analytical Standards, Analytical/Chromatography, Antagonists, Approved Therapeutics/Drug Candidates, B, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Chemical Structure, Chromatography, Drugs & Metabolites, Drugs of Abuse, Forensic and Veterinary Standards, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, GlaxoSmithKline, Membrane Protein Biology Tools, Neat Compounds, Neuroscience, Neurotransmission, Neurotransmitters,
{SNA} Adrenergics,
产品应用
Selective ?2A-adrenoceptor antagonist . Increases hippocampal noradrenaline release following systemic administration.
相关文献及参考
Young, et al.: Eur. J. Pharmacol., 168, 381 (1989),
Kiss, et al.: Brain Res., 238, 674 (1995),
Callado, et al.: Eur. J. Pharmacol., 35, 366 (1999),
Willems, et al. Br. J. Pharmacol. 132 , 1292-1298, (2001) 摘要
安全信息
WGK Germany
3
Personal Protective Equipment
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
系列性分类
Analytical & Chromatography 分析化学与色谱
Analytical Standards
Chromatography - Analytical Standards
Forensic and Veterinary Standards - Chromatography
Drugs & Metabolites - Forensic and Veterinary Standards
Analytical & Chromatography 分析化学与色谱
Analytical Standards
Chromatography - Analytical Standards
Forensic and Veterinary Standards - Chromatography
Drugs of Abuse - Forensic and Veterinary Standards
Chemical Structure - Drugs of Abuse
Others - Chemical Structure
Life Science 生命科学
Biochemicals and Reagents 生化试剂
Proteins and Derivatives - Biochemicals and Reagents
Membrane Protein Biology Tools - Proteins and Derivatives
GPCR Proteins, Modulators and Antibodies - Membrane Protein Biology Tools
GPCR Modulators - GPCR Proteins, Modulators and Antibodies
Adrenergics - Antagonists - GPCR Modulators
Functional Group 官能团索引
carboxylic acid amidine
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