Fenoldopam Hydrobromide

CAS 67287-54-1 MFCD02684405

化学结构图

67287-54-1
SMILES: Br.OC1=CC2[C@H](CNCCC=2C(Cl)=C1O)C1C=CC(O)=CC=1

化学属性

Mol. FormulaC16H17BrClNO3
Mol. Weight386.67

别名和识别编码

Chemical NameFenoldopam Hydrobromide
CAS Number67287-54-1
Synonym 6-Chloro-2,3,4,5-tetrahydro-1-(4-hydroxyphenyl)-1H-3-benzazepine-7,8-diol Hydrobromide (?)-Fenoldopam Hydrobromide (?)-SKF 82526 Hydrobromide SKF 82526 Hydrobromide 6-Chloro-2,3,4,5-tetrahydro-1-(4-hydroxyphenyl)-1H-3-benzazepine-7,8-diol monohydrobromide SKF-82526
PubChem Substance ID24278441
EC Number266-634-7
Chemical Name Translation
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • Agonists
  • Aromatics
  • Heterocycles
  • Neurochemicals
  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • {SA} A to C, Agonists, Angiotensin Converting Enzyme, Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Dopaminergics, Dopaminergics - Agonists, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, F, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, Hospira, Membrane Protein Biology Tools, Neuroscience, Neurotransmission, Neurotransmitters, Protease Inhibitor Specificity Index, Protease Inhibitors,

产品应用

  • Dopamine D1-receptor agonist. Antihypertensive.

相关文献及参考

  • Ballo, A. et al.: J. Neurosci., 30, 8425 (2010); Stote, R.M., et al.: Clin. Pharmacol. Ther., 34, 309 (1983); Carey, M., et al.: J. Clin. Invest., 74, 2198 (1984); Caruana, M.P., et al.: Br. J. Clin.
  • Hahn, R.A., et al., Characterization of the peripheral and central effects of SK&F 82526a novel dopamine receptor agonist. J. Pharmacol. Exp. Ther. 223 , 305-313, (1982) 摘要
  • Hussain, T., and Lokhandwala, M.F., Renal dopamine DA1 receptor coupling with G(S) and G(q/11) proteins in spontaneously hypertensive rats. Am. J. Physiol. 272 , F339-F346, (1997) 摘要
  • Venkatakrishnan, U., et al., The role of intrarenal nitric oxide in the natriuretic response to dopamine-receptor activation. Clin. Exp. Hypertens. 22 , 309-324, (2000) 摘要
  • Quevedo, M., et al., The effect of fenoldopam on the blood pressure of the rat. Gen. Pharmacol. 32 , 123-125, (1999) 摘要
  • deVries, P.A., et al., Impaired renal vascular response to a D1-like receptor agonist but not to an ACE inhibitor in conscious spontaneously hypertensive rats. J. Cardiovasc. Pharmacol. 34 , 191-198, (1999) 摘要
  • Merck 14 ,3979

安全信息

GHS Symbol
WGK Germany3
Hazard statements
  • H317 May cause an allergic skin reaction 可能导致皮肤过敏
  • H302 Harmful if swallowed 吞食有害
  • H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled 吸入可能导致过敏或哮喘症状或呼吸困难
  • H319 Causes serious eye irritation 严重刺激眼睛
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Hazard Codes Xn
Precautionary statements
  • P342+P311
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P305+P351+P338
Signal word Danger

系列性分类

  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Enzyme Inhibitors - Enzymes, Inhibitors, and Substrates
  5. Enzyme Inhibitors by Enzyme - Enzyme Inhibitors
  6. A to C - Enzyme Inhibitors by Enzyme
  7. Angiotensin Converting Enzyme - A to C
  1. Functional Group 官能团索引
  2. 1,2-diphenol

相关产品推荐