Acylase I 酰化氨基酸水解酶

CAS 9012-37-7 MFCD00081285

化学结构图

9012-37-7
SMILES: O=C(CCCCCCNc1c2c(nc3cc(Cl)cc(Cl)c13)CCCC2)NCCc1c[nH]c2ccccc12

化学属性

Mol. Formula
Mol. Weight-

别名和识别编码

Synonym Acylase Acylase ‘Amano’ Aminoacylase Acylase I Acylase I from Aspergillus melleus Acylase I from porcine kidney Amino acid deacylase Aminoacylase N-Acylamino acid amidohydrolase Aminoacylase I Aminoacylase, immobilized Plexazym® AC Benzamidase Dehydropeptidase II E.C. 3.5.1.14 Hippurase Hippuricase Histozyme L-Amino acid acylase L-Aminoacylase L-氨基酰化酶 alpha-N-Acylamino acid hydrolase 酰化酶
MDL NumberMFCD00081285
CAS Number9012-37-7
EC Number232-732-3
PubChem Substance ID11706508
Chemical NameAcylase I
Chemical Name Translation酰化氨基酸水解酶
InChIInChI=1S/C30H34Cl2N4O/c31-21-17-24(32)29-27(18-21)36-26-12-7-5-10-23(26)30(29)34-15-8-2-1-3-13-28(37)33-16-14-20-19-35-25-11-6-4-9-22(20)25/h4,6,9,11,17-19,35H,1-3,5,7-8,10,12-16H2,(H,33,37)(H,34,36)
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分类

  • {SNA} 3.5.x.x Acting on C-N other than peptides, 3.x.x.x Hydrolases, Biochemicals and Reagents, Chemical Synthesis, Enzyme Class Index, Enzyme-Mediated Synthesis, Enzymes, Inhibitors, and Substrates, General Metabolic Enzymes, General Metabolic Enzymes A-H, Hydrolases, Metabolomics, Specialty Synthesis
  • 3.5.x.x Acting on C-N other than peptides, 3.x.x.x Hydrolases, Application Index, Biochemicals and Reagents, Enzyme Class Index, Enzymes, Inhibitors, and Substrates, General Metabolic Enzymes, Lipid Metabolism, Metabolomics, Organic Synthesis, Organic Synthesis and Immobilized Enzymes
  • {SNA} 3.5.x.x Acting on C-N other than peptides,

相关文献及参考

  • 1. D. Jaworek et al. Meth. Enzymol. 44 , 195, (1976) 摘要
  • 2. W. Kuhlmann et al. Chem. Ing. Tech. 52 , 607, (1980)
  • 3. J. Tramper Solid Phase Biochemistry New York , 393, (1983)
  • 4. T. Sato, T. Tosa Bioprocess Technol. 16 , 3, (1993) 摘要

安全信息

RTECSBF4890000
GHS Symbol
Precautionary statements
  • P342+P311
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
Signal word Danger
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled 吸入可能导致过敏或哮喘症状或呼吸困难
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Storage condition 0-10 <0°C 贮存温度-20℃ 0-10°C <;0
Safety Statements
  • S24 Avoid contact with skin 避免皮肤接触；
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
  • S22 Do not breathe dust 不要吸入粉尘；
Hazard Codes Xn
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R42 May cause sensitisation by inhalation 吸入会产生过敏反应
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 5 mg/plate
REFERENCE :
   AOISDR Annual Report of Osaka City Institute of Public Health and
   Environmental Sciences.  (Osaka- shiritsu Kankyo Kagaku Kenkyusho, 8-34
   Tojo-cho, Tennoji-ku, Osaka 543, Japan) No.42-    1981-
   Volume(issue)/page/year: (47),24,1985

其他信息

  • Enzyme Commission (EC) Number: 3.5.1.14 ( BRENDA | IUBMB )

系列性分类

  1. Life Science 生命科学
  2. Metabolomics 代谢组学
  3. General Metabolic Enzymes - Metabolomics
  4. General Metabolic Enzymes A-H - General Metabolic Enzymes
  1. Life Science 生命科学
  2. Metabolomics 代谢组学
  3. General Metabolic Enzymes - Metabolomics
  4. Lipid Metabolism - General Metabolic Enzymes
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Application Index - Enzymes, Inhibitors, and Substrates
  5. Organic Synthesis and Immobilized Enzymes - Application Index
  6. Immobilized Enzymes - Organic Synthesis and Immobilized Enzymes
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Application Index - Enzymes, Inhibitors, and Substrates
  5. Organic Synthesis and Immobilized Enzymes - Application Index
  6. Organic Synthesis - Organic Synthesis and Immobilized Enzymes
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Enzyme Class Index - Enzymes, Inhibitors, and Substrates
  5. 3.x.x.x Hydrolases - Enzyme Class Index
  6. 3.5.x.x Acting on C-N other than peptides - 3.x.x.x Hydrolases
  1. Life Science 生命科学
  2. Biochemistry / Glyco-Chemistry
  3. Enzyme

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