Lipase 脂肪酶

CAS 9001-62-1 MFCD00131509

化学结构图

9001-62-1
SMILES: Oc1ccc(N=Nc2ccccn2)c(O)c1.[Na+]

化学属性

Mol. Formula
Mol. Weight-
Stability对热和湿度敏感
Density1.140000
Appearance off-white immobilized granulate yellow to light-brown liq. yellow liq. brown liq. brown immobilized granulate

别名和识别编码

MDL NumberMFCD00131509
CAS Number9001-62-1
EC Number232-619-9
Merck Number5511
Synonym Amano N-AP Butyrinase CCL Glycerol ester hydrolase Lipase A Candida antarctica, recombinant from Aspergillus oryzae Lipase F-AP 15 Lipazin Lipolase 100L NovoCor AD L Remzyme PL 600 Steapsin Triacetinase Triacylglycerol acylhydrolase, Triacylglycerol lipase Triacylglycerol hydrolase Triacylglycerol lipase Tributyrinase Tween hydrolase Tweenase 三酰基甘油酰基水解酶 三酰基甘油酰基水解酶;PPL;三酰基甘油脂肪酶 脂肪酶 脂肪酶 来源于嗜热栖热菌 脂肪酶 来源于念珠菌 属 脂肪酶 来源于皱褶假丝酵母 脂肪酶 来源于米曲霉 脂肪酶 来源于米黑毛霉菌 脂肪酶 来源于雪白根霉菌
Chemical NameLipase
Chemical Name Translation脂肪酶
PubChem Substance ID135534490
InChIInChI=1S/C11H9N3O2.Na/c15-8-4-5-9(10(16)7-8)13-14-11-3-1-2-6-12-11;/h1-7,15-16H;/q;+1
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • {SNA} 3.1.x.x Acting on esters, 3.x.x.x Hydrolases, Biochemicals and Reagents, Enzyme Class Index, 酶、抑制剂和底物
  • {SNA} 3.1.x.x Acting on esters, 3.x.x.x Hydrolases, Analytical and Industrial Enzymes, Biochemicals and Reagents, Enzyme Class Index, Novozymes: Quality Environmentally-Friendly Enzymes, 酶、抑制剂和底物
  • {SNA} 3.1.x.x Acting on est

产品应用

  • Usually used industrially for the resolution of chiral compounds and the transesterification production of biodiesel.

相关文献及参考

  • Merck: 14,5511
  • 2. S. Gedey et al., Preparation of highly enantiopure β-amino esters by Candida Antarctica lipase A Tetrahedron Asymmetry 12 , 105-110, (2001)

安全信息

WGK Germany1
RTECSTO9776500
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Storage condition -20°C保存，干冰运输 储存温度-20°C,充氩保存 储存温度2-8°C,充氩保存 0-10°C 0-10 储存温度-20°C
Hazard Codes B
GHS Symbol
Safety Statements
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
Precautionary statements
  • P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛，皮肤或衣服。
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >10400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NYKZAU Nippon Yakurigaku Zasshi.  Japanese Journal of Pharmacology. (Nippon
   Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho,
   Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40-    1944- Volume(issue)/page/year:
   69,191,197

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 630 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
   Lungs, Thorax, or Respiration - respiratory stimulation
   Blood - hemorrhage
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 13,906,1979

TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >5 gm/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - ptosis
   Behavioral - somnolence (general depressed activity)
   Skin and Appendages - hair

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 127 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
   Lungs, Thorax, or Respiration - respiratory stimulation
   Kidney, Ureter, Bladder - other changes
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 56 gm/kg
SEX/DURATION            : female 8-14 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
   Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured
   before birth)
REFERENCE :
   NYKZAU Nippon Yakurigaku Zasshi.  Japanese Journal of Pharmacology. (Nippon
   Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho,
   Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40-    1944- Volume(issue)/page/year:
   70,107,1974

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 4550 gm/kg
SEX/DURATION            : male 26 week(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland,
   accessory glands
REFERENCE :
   NYKZAU Nippon Yakurigaku Zasshi.  Japanese Journal of Pharmacology. (Nippon
   Yakuri Gakkai, c/o Kyoto Dai

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 56 gm/kg
SEX/DURATION            : female 7-13 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
   Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured
   before birth)
REFERENCE :
   NYKZAU Nippon Yakurigaku Zasshi.  Japanese Journal of Pharmacology. (Nippon
   Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho,
   Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40-    1944- Volume(issue)/page/year:
   70,107,1974

其他信息

  • 能使脂肪水解为脂肪酸和甘油的酶，生成脂肪酸、甘油和甘油单酯或二酯。

系列性分类

  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Analytical Enzymes - Enzymes, Inhibitors, and Substrates
  5. Novozymes: Quality Environmentally-Friendly Enzymes - Analytical Enzymes
  1. Life Science 生命科学
  2. Metabolomics 代谢组学
  3. General Metabolic Enzymes - Metabolomics
  4. Lipid Metabolism - General Metabolic Enzymes
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Application Index - Enzymes, Inhibitors, and Substrates
  5. Diagnostic and Analytical Enzymes - Application Index
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Application Index - Enzymes, Inhibitors, and Substrates
  5. Diagnostic and Analytical Enzymes - Application Index
  1. Chemical Synthesis 化学合成
  2. Specialty Synthesis 特殊合成技术
  3. Enzyme-Mediated Synthesis - Specialty Synthesis
  4. Hydrolases - Enzyme-Mediated Synthesis
  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Standards
  3. Alphabetic - Analytical Standards
  4. H - Alphabetic
  5. HU - HZ - H
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Application Index - Enzymes, Inhibitors, and Substrates
  5. Organic Synthesis and Immobilized Enzymes - Application Index
  6. Immobilized Enzymes - Organic Synthesis and Immobilized Enzymes
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Enzyme Class Index - Enzymes, Inhibitors, and Substrates
  5. 3.x.x.x Hydrolases - Enzyme Class Index
  6. 3.1.x.x Acting on esters - 3.x.x.x Hydrolases
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Enzyme Class Index - Enzymes, Inhibitors, and Substrates
  5. 3.x.x.x Hydrolases - Enzyme Class Index
  6. Others - 3.x.x.x Hydrolases
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Enzyme Class Index - Enzymes, Inhibitors, and Substrates
  5. 3.x.x.x Hydrolases - Enzyme Class Index
  6. Others - 3.x.x.x Hydrolases
  1. Life Science 生命科学
  2. Biochemistry / Glyco-Chemistry
  3. Enzyme
  1. Biocatalyst
  2. Biocatalysts
  1. Catalysts
  2. Biocatalysts
  1. Biocatalyst
  2. 96-0220 Novozymes Lipase Screening Kit (contains 9 lipase enzymes)
  1. Catalysts
  2. 96-0220 Novozymes Lipase Screening Kit (contains 9 lipase enzymes)

相关产品推荐