Bimatoprost 比马前列素

CAS 155206-00-1 MFCD03411999

化学结构图

155206-00-1
SMILES: CCNC(=O)CCC/C=C\C[C@@H]1[C@@H](/C=C/[C@@H](O)CCC2C=CC=CC=2)[C@H](O)C[C@@H]1O

化学属性

Mol. FormulaC25H37NO4
Mol. Weight415.57

别名和识别编码

Chemical NameBimatoprost
CAS Number155206-00-1
Synonym (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-N-ethyl-5-heptenamide 17-Phenyl-tri-norprostaglandin F2α-ethyl amide AGN-192024 Bimatoprost Lumigan Prostamide
MDL NumberMFCD03411999
Chemical Name Translation比马前列素
PubChem Substance ID329820253
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分类

  • Pharmaceuticals
  • {SNA} Arachidonic Acid Cascade, Cell Biology, Cell Signaling and Neuroscience, Lipids in Cell Signaling, Prostaglandins
  • Chiral Reagents
  • {SNA} Arachidonic Acid Cascade, Bioactive Small Molecule Alphabetical Index, Lipids in Cell Signaling, P-PH, Prostaglandins, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
  • Intermediates & Fine Chemicals,

产品应用

  • Bimatoprost is an antiglaucoma agent. Bimatoprost is an synthetic prostamide; structurally related to prostaglandin F2?.

相关文献及参考

  • [2]. Filippopoulos T, et al. Periorbital changes associated with topical bimatoprost. Ophthal Plast Reconstr Surg. 2008 Jul-Aug;24(4):302-7.
  • Brandt, J.D., et al.: Ophthalmology, 108, 1023 (2001),
  • Quinones, R., et al.: J. Ocul. Pharmacol. Ther., 20, 115 (2004),
  • Woodward, D.F., et al.: J. Pharmacol. Exp. Ther., 305, 772 (2003),
  • [1]. Park J, et al. Changes to upper eyelid orbital fat from use of topical bimatoprost, travoprost, and latanoprost. Jpn J Ophthalmol. 2011 Jan;55(1):22-7.
  • [1]. Park J, et al. Changes to upper eyelid orbital fat from use of topical bimatoprost, travoprost, and latanoprost. Jpn J Ophthalmol. 2011 Jan;55(1):22-7.
  • [2]. Filippopoulos T, et al. Periorbital changes associated with topical bimatoprost. Ophthal Plast Reconstr Surg. 2008 Jul-Aug;24(4):302-7.

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

系列性分类


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