2-[(2-1H-INDOL-3-YL-ACETYL)-METHYLAMINO]-N-(4-ISOPROPYLPHENYL)-2-PHENYLACETAMIDE
CAS 853138-65-5 MFCD03449821
化学结构图
SMILES: CC(C)C1C=CC(=CC=1)NC(=O)C(C1C=CC=CC=1)N(C)C(=O)CC1=CNC2C=CC=CC=21
化学属性
| Mol. Formula | C28H29N3O2 |
|---|---|
| Mol. Weight | 439.55 |
别名和识别编码
| Chemical Name | PG-01 |
|---|---|
| Synonym | 2-[(2-1H-indol-3-yl-acetyl)-methylamino]-N-(4-isopropylphenyl)-2-phenylacetamide 2-[(2-1H-indol-3-yl-acetyl)-methylamino]-N-(4-isopropylphenyl)-2-phenylacetamide N-Methyl-N-[2-[[4-(1-methylethyl)phenyl]amino]-2-oxo-1-phenylethyl]-1H-indole-3-acetamide N-Methyl-N-[2-[[4-(1-methylethyl)phenyl]amino]-2-oxo-1-phenylethyl]-1H-indole-3-acetamide |
| MDL Number | MFCD03449821 |
| CAS Number | 853138-65-5 |
| PubChem Substance ID | 329819979 |
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分类
- Cell Biology, Cell Signaling and Neuroscience, Chloride Channel Modulators, Ion Channels, Monovalent Ion Channels, Voltage-gated Ion Channels
- {SNA} Bioactive Small Molecule Alphabetical Index, Chloride Channel Modulators, Ion Channels, Monovalent Ion Channels, P-PH, Voltage-gated Ion Channels,
相关文献及参考
- Caputo, A., et al., Mutation-specific potency and efficacy of CFTR chloride channel potentiators. J. Pharmacol. Exp. Ther. , (2009)
- Pedemonte, N., et al., Phenylglycine and sulfonamide correctors of defective ΔF508 and G551D cystic fibrosis transmembrane conductance regulator chloride-channel gating. Mol. Pharmacol. 67 , 1797-1807, (2005)
安全信息
GHS Symbol
- H413 Maycauselonglastingharmfuleffectstoaquaticlife 可能对水生生物造成长期持续有害影响。
- H302 Harmful if swallowed 吞食有害
- R22 Harmful if swallowed 吞咽有害
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