1-methyl-5-propyl-1H-pyrazole-3-carboxylic acid 1-methyl-5-propyl-1H-pyrazole-3-carboxylic acid

CAS 247583-70-6 MFCD04115071

化学结构图

247583-70-6
SMILES: CCCC1=CC(=NN1C)C(O)=O

化学属性

Mol. FormulaC8H12N2O2
Mol. Weight168
Density1.422
Melting Point106-112

别名和识别编码

Chemical Name1-methyl-5-propyl-1H-pyrazole-3-carboxylic acid
CAS Number247583-70-6
MDL NumberMFCD04115071
EC Number250-023-7
Beilstein Registry Number2384789
Chemical Name Translation1-methyl-5-propyl-1H-pyrazole-3-carboxylic acid
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分类

  • Heterocycles
  • Pharmaceuticals
  • Intermediates & Fine Chemicals

产品应用

  • Intermediate in the preparation of Iso Viagra, Sidenafil analogs and pyrazolopyrimidinone cGMP PDE5 inhibitors for the treatment of sexual dysfunction.

相关文献及参考

  • El-Abadelah, M. et al.; J. Heterocyclic Chem. 39, 1055 (2002); Kopp, M. et al.; J. Heterocyclic Chem. 38, 1045 (2001)

安全信息

Signal word Warning
GHS Symbol
WGK Germany3
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S7/47 Keep container tightly closed and at temperature not exceeding ... °C (to be specified by the manufacturer) 保持容器严格密闭,温度不超过….°C(由生产厂家指定);
Risk Statements
  • R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
Precautionary statements
  • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前,切勿操作。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。

系列性分类


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