(Z)-3-((1H-Imidazol-4-yl)methylene)-5-methoxyindolin-2-one (Z)-3-((1H-咪唑-4-基)亚甲基)-5-甲氧基吲哚啉-2-酮

CAS 377090-84-1 MFCD05865243

化学结构图

377090-84-1
SMILES: COC1=CC2/C(=C/C3=CNC=N3)/C(=O)NC=2C=C1

化学属性

Mol. FormulaC13H11N3O2
Mol. Weight241.25

别名和识别编码

Chemical Name(Z)-3-((1H-Imidazol-4-yl)methylene)-5-methoxyindolin-2-one
MDL NumberMFCD05865243
PubChem Substance ID24278633
CAS Number377090-84-1
Chemical Name Translation(Z)-3-((1H-咪唑-4-基)亚甲基)-5-甲氧基吲哚啉-2-酮
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分类

  • {SA} A to C, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Cyclin Dependant Kinase 2, Cyclin-Dependent Kinase (CDK), Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, Kinase/Phosphatase Biology, Protein Kinase Inhibitors, S, Serine/Threonine Kinase Biology, Serine/Threonine Kinase Inhibitors
  • {SNA} A to C, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Cyclin Dependant Kinase 2, Cyclin-Dependent Kinase (CDK), Enzyme Inhibitors,

相关文献及参考

  • Yu, B., et al, SU9516, a cyclin-dependent kinase 2 inhibitor, promotes accumulation of high molecular weight E2F complexes in human colon carcinoma cells. Biochem. Pharmacol. 64 , 91-100, (2002) 摘要
  • Lane, M.E., et al, . A novel cdk2-selective inhibitor, SU9516, induces apoptosis in colon carcinoma cells. Cancer Res. 61 , 6170-6177, (2001)

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

系列性分类


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