2,6-Diamino-4-(Piperidin-1-yl)Pyrimidine 1-Oxide Sulfate 6-氨基-1,2-二氢-1-羟基-2-亚胺基-4-(1-哌啶基)嘧啶硫酸酯盐

CAS 83701-22-8 MFCD06248907

化学结构图

83701-22-8
SMILES: NC1=NC(=CC(N)=[N+]1OS([O-])(=O)=O)N1CCCCC1

化学属性

Mol. FormulaC9H15N5O4S
Mol. Weight289.31

别名和识别编码

Chemical Name2,6-Diamino-4-(Piperidin-1-yl)Pyrimidine 1-Oxide Sulfate
CAS Number83701-22-8
Synonym 1,6-Dihydro-6-imino-4-(1-piperidinyl)-1-(sulfooxy)- 6-(1-Piperidinyl)-2,4-pyrimidinediamine-3-oxide Sulfate Minoxidil sulfate salt U-58838
MDL NumberMFCD06248907
PubChem Substance ID24897202
Chemical Name Translation6-氨基-1,2-二氢-1-羟基-2-亚胺基-4-(1-哌啶基)嘧啶硫酸酯盐
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分类

  • {SNA} Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Ion Channels, Johnson & Johnson, M, Monovalent Ion Channels, Potassium Channel Modulators, Voltage-gated Ion Channels, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
  • Heterocycles
  • Glucuronides
  • Pharmaceuticals
  • Amines
  • {SNA} Approved Therapeutic

产品应用

  • Minoxidil sulfate is the active metabolite of Minoxidil and is a potent (IC50=0.14?M) vascular smooth muscle relaxant. Minoxidil sulfate is a selective ATP-sensitive potassium channel opener.

相关文献及参考

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安全信息

WGK Germany3
GHS Symbol
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H302 Harmful if swallowed 吞食有害
  • H319 Causes serious eye irritation 严重刺激眼睛
Signal word Warning
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36 Wear suitable protective clothing 穿戴适当的防护服；
Hazard Codes Xn
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R22 Harmful if swallowed 吞咽有害

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Approved Therapeutics/Drug Candidates - Cell Signaling and Neuroscience
  5. Johnson & Johnson - Approved Therapeutics/Drug Candidates
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Ion Channels - Cell Signaling and Neuroscience
  5. Voltage-gated Ion Channels - Ion Channels
  6. Monovalent Ion Channels - Voltage-gated Ion Channels
  7. Potassium Channel Modulators - Monovalent Ion Channels

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