Bafilomycin A1 巴佛洛霉素 A1

CAS 88899-55-2 MFCD06795130

化学结构图

88899-55-2
SMILES: CC(C)[C@H]1O[C@](O)(C[C@@H](O)[C@@H]1C)[C@@H](C)[C@H](O)[C@H](C)[C@H]1OC(=O)C(=CC(C)=C[C@@H](C)[C@@H](O)[C@@H](C)CC(C)=CC=C[C@@H]1OC)OC |t:23,26,36,38|

化学属性

Mol. FormulaC35
Mol. Weight623

别名和识别编码

Chemical NameBafilomycin A1
MDL NumberMFCD06795130
PubChem Substance ID24891613
Beilstein Registry Number4730700
CAS Number88899-55-2
Synonym Bafilomycin A1 from Streptomyces griseus
Chemical Name Translation巴佛洛霉素 A1
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分类

  • {SA} Antibiotics, Antibiotics A to Z, Antibiotics A-F,
  • Antibiotics, Antibiotics A to Z, Antibiotics A-F, Antibiotics by Application, Antifungal, Antineoplastic and Immunosuppressive Antibiotics, Autophagy, Autophagy Inhibitors, B, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Chemical Structure Class, Inhibits an Enzyme, Interferes with DNA Synthesis, Ion Channels, Ion Pump Inhibitors, Macrolides, Mechanism of Action, Monovalent Ion Channels, Spectrum of Activity, Voltage-gated Ion Channels
  • {SNA} Antibiotics A to Z,

相关文献及参考

  • Bowman, E.J., et al. Proc. Natl. Acad. Sci. U. S. A. 85 , 7972, (1988) 摘要
  • Umata, T., et al. J. Biol. Chem. 265 , 21940, (1990) 摘要
  • Yoshimori, T., et al. J. Biol. Chem. 266 , 17707, (1991) 摘要
  • Saurin, A.J., et al. Biochem. J. 313 , 65, (1996) 摘要
  • Rainey, M.M., et al., The Antidepressant Sertraline Targets Intracellular Vesiculogenic Membranes In Yeast. Genetics 185 , 1221-33, (2010) 摘要

安全信息

Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
GHS Symbol
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Hazard Codes Xi
WGK Germany3
Signal word
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36 Wear suitable protective clothing 穿戴适当的防护服；
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性

系列性分类

  1. Life Science 生命科学
  2. Antibiotics 抗生素
  3. Antibiotics A to Z - Antibiotics
  4. Antibiotics A-F - Antibiotics A to Z
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Bioactive Small Molecules - Cell Biology
  4. B - Bioactive Small Molecules
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Ion Channels - Cell Signaling and Neuroscience
  5. Voltage-gated Ion Channels - Ion Channels
  6. Monovalent Ion Channels - Voltage-gated Ion Channels
  7. Ion Pump Inhibitors - Monovalent Ion Channels
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Antibiotics
  4. Antibiotics by Application
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Antibiotics
  4. Mechanism of Action
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Antibiotics
  4. Chemical Structure Class
  5. Indol Derivatives
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Antibiotics
  4. Mechanism of Action
  5. Interferes with Cell Wall Synthesis
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Antibiotics
  4. Spectrum of Activity
  5. Antibacterial
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Antibiotics
  4. Spectrum of Activity
  5. Antibacterial
  6. L - Z
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Cell Signaling and Neuroscience
  4. Ion Channels
  5. Voltage-gated Ion Channels
  6. Monovalent Ion Channels
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Cell Signaling and Neuroscience
  4. Neuroscience
  5. Ion Channels
  6. Ligand-Gated Ion Channels

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