Levocabastine hydrochloride

CAS 79547-78-7 MFCD07787408

化学结构图

79547-78-7
SMILES: Cl.C[C@H]1CN(CC[C@@]1(C(O)=O)C1=CC=CC=C1)[C@@H]1CC[C@@](CC1)(C#N)C1=CC=C(F)C=C1

化学属性

Mol. FormulaC26H29N2O2F·HCl
Mol. Weight457

别名和识别编码

Chemical NameLevocabastine hydrochloride
CAS Number79547-78-7
Synonym Levocabastine hydrochloride ######## Levophta Levostin R50547 [3S-[1(cis),3α,4β]]-1-[4-cyano-4-(4-fluorophenyl)cyclohexyl]-3-methyl-4-phenyl-4-piperidinecarboxylic acid Levophta Levostin R50547 [3S-[1(cis),3α,4β]]-1-[4-cyano-4-(4-fluorophenyl)cyclohexyl]-3-methyl-4-phenyl-4-piperidinecarboxylic acid
MDL NumberMFCD07787408
Chemical Name Translation
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • {SNA} Antagonists, Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, Histaminergics, Histaminergics - Antagonists, Johnson & Johnson, L, Membrane Protein Biology Tools, Neuroscience, Neurotransmission, Neurotransmitters, 生化试剂, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学, 蛋白质及衍生物
  • Chiral Reagents
  • Heterocycles
  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • Aromatics
  • {SNA} Antagonists, Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience

产品应用

  • A histamine H1 receptor antagonist

相关文献及参考

  • [2]. Yamauchi R, et al. Effect of beta-lactotensin on acute stress and fear memory. Peptides. 2006;27(12):3176-3182.
  • Ash, A., et al.: Br. J. Pharmacol., 27, 427 (1966),
  • Davies, M., et al.: Br. J. Clin. Pharmacol., 9, 461 (1980),
  • Oda, T., et al.: J. Biol. Chem., 275, 36781 (2000),
  • [1]. Folkerts G, et al. Virus-induced airway hyperresponsiveness in the guinea-pig: possible involvement of histamine and inflammatory cells. Br J Pharmacol. 1993;108(4):1083-1093.
  • [1]. Folkerts G, et al. Virus-induced airway hyperresponsiveness in the guinea-pig: possible involvement of histamine and inflammatory cells. Br J Pharmacol. 1993;108(4):1083-1093.
  • [2]. Yamauchi R, et al. Effect of beta-lactotensin on acute stress and fear memory. Peptides. 2006;27(12):3176-3182.

安全信息

GHS Symbol
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
WGK Germany3
Signal word Warning
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36 Wear suitable protective clothing 穿戴适当的防护服；
Hazard Codes Xi
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Bioactive Small Molecules - Cell Biology
  4. L - Bioactive Small Molecules
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Approved Therapeutics/Drug Candidates - Cell Signaling and Neuroscience
  5. Johnson & Johnson - Approved Therapeutics/Drug Candidates
  1. Medical Research Areas
  2. GPCR & G Protein
  3. Histamine Receptor  (组胺受体)
  1. Medical Research Areas
  2. GPCR & G Protein
  3. Neurotensin Receptor  (神经降压素受体)

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