Latanoprost Acid 拉坦前列素酸
CAS 41639-83-2 MFCD08056084
化学结构图
SMILES: OC(=O)CCC/C=C\C[C@@H]1[C@@H](CC[C@@H](O)CCC2C=CC=CC=2)[C@H](O)C[C@@H]1O
化学属性
| Mol. Formula | C23H34O5 |
|---|---|
| Mol. Weight | 390.51 |
别名和识别编码
| Chemical Name | Latanoprost Acid |
|---|---|
| CAS Number | 41639-83-2 |
| Synonym | (5Z)- (5Z,9α,11α,15R)-9,11,15-Trihydroxy-17-phenyl-18,19,20-trinor-prost-5-en-1-oic acid PhXA 85 (5Z,9α,11α,15R)-9,11,15-Trihydroxy-17-phenyl-18,19,20-trinor-prost-5-en-1-oic acid (5Z,9α,11α,15R)-9,11,15-Trihydroxy-17-phenyl-18,19,20-trinor-prost-5-en-1-oic acid (Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]hept-5-enoic acid PhXA 85 (Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]hept-5-enoic acid Latanoprost acid PhXA 85 |
| MDL Number | MFCD08056084 |
| PubChem Substance ID | 24724524 |
| Chemical Name Translation | 拉坦前列素酸 |
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分类
- {SNA} Approved Therapeutics/Drug Candidates, Arachidonic Acid Cascade, Bioactive Small Molecule Alphabetical Index, Fluorination Ready Pharma-Developed Compounds, Johnson & Johnson, L, Lipids in Cell Signaling, Prostaglandins, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
- Chiral Reagents
- Pharmaceuticals
- {SNA} Approved Therapeutics/Drug Candidates, Arachidonic Acid Cascade, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Johnson & Johnson, L, Lipids in Cell Signaling, Prostaglandins
- Aromatics
- Intermediates & Fine Chemicals,
- Metabolites & Impurities
产品应用
- A metabolite of Latanoprost
相关文献及参考
- [2]. Xu X, et al. The prevention of latanoprost on osteoclastgenesis in vitro and lipopolysaccharide-induced murine calvaria osteolysis in vivo. J Cell Biochem. 2018 Jun;119(6):4680-4691.
- Sjoquist, B., et al.: Drug Metab. Dispos., 26, 745
- [1]. Weinreb RN, et al. Effects of prostaglandins on the aqueous humor outflow pathways. Surv Ophthalmol. 2002 Aug;47 Suppl 1:S53-64.
- [1]. Weinreb RN, et al. Effects of prostaglandins on the aqueous humor outflow pathways. Surv Ophthalmol. 2002 Aug;47 Suppl 1:S53-64.
- [2]. Xu X, et al. The prevention of latanoprost on osteoclastgenesis in vitro and lipopolysaccharide-induced murine calvaria osteolysis in vivo. J Cell Biochem. 2018 Jun;119(6):4680-4691.
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